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REPS1 is a signaling adaptor protein with two EH domains that interacts with proteins that participate in signaling, endocytosis and cytoskeletal changes. The encoded protein has been found in association with intersectin 1 and Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1 when intersectin 1 was isolated from clathrin-coated pits. The encoded protein has also been shown to interact with amphiphysin, a cytoplasmic protein at the surface of synaptic vesicles. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Name: | RALBP1 Associated Eps Domain Containing 1 |
Synonyms: | REPS1, RalBP1-interacting protein 1 |
Target Sequences: | NM_031922 NP_114128.3 Q96D71 |
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