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REN / Renin 1
Renin
Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.
| Gene Name: | Renin |
| Family/Subfamily: | Protease , Aspartic A1 |
| Synonyms: | REN, Angiotensin-forming enzyme, Angiotensinogenase, HNFJ2, RENAA, Renin precursor, renal, Renin |
| Target Sequences: | NM_000537 NP_000528.1 P00797 |
Publications (3)
1
Heart Failure With Reduced Ejection Fraction Is Characterized by Systemic NEP Downregulation. Imre J Pavo, Noemi Pavo, Nina Kastner, Denise Traxler, Dominika Lukovic, Katrin Zlabinger, Andreas Spannbauer, Martin Riesenhuber, David Lorant, Philipp E Bartko, Georg Goliasch, Martin Hülsmann, Johannes Winkler, Mariann Gyöngyösi. JACC. Basic to translational science. 2020 July;5:715-726. [Full Text Article]
[PubMed:32760858]
[PMC:PMC7393434]
2
Full Issue PDF. No authors listed. JACC. Basic to translational science. 2020 July;5:I-CX. [Full Text Article]
[PubMed:32835137]
[PMC:PMC7384789]
3
Comparison of the expression of neurotransmitter and muscular genesis markers in the postnatal male mouse masseter and trigeminal ganglion during development. Hiroaki Kamata, Hiroyuki Karibe, Iwao Sato. Journal of neuroscience research. 2018 June;96:1043-1055. [Full Text Article]
[PubMed:29265492]
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REN / Renin 1 Mouse anti-Human Monoclonal (6E2-B7) Antibody
Dog, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
REN / Renin 1 Mouse anti-Human Monoclonal (7D3-E3) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460; 100 µg/$485
REN / Renin 1 Sheep anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$525
REN / Renin 1 Mouse anti-Human Monoclonal (aa24-406) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$941
REN / Renin 1 Goat anti-Mouse Polyclonal (aa22-402) Antibody
Mouse
ELISA, IP, WB
Unconjugated
100 µg/$962
REN / Renin 1 Sheep anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$589; 1 mg/$4,032
REN / Renin 1 Mouse anti-Human Monoclonal (3B5) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Sandwich
96-Well Microplate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$699
Sandwich
96-Well Microplate
Mouse
12.21 - 50000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$840
Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Sandwich
96-Well Microplate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
Sandwich
96-Well Strip Plate
Pig
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
REN / Renin 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$397
Sandwich
96-Well Strip Plate
Monkey
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$565
REN / Renin 1 Rabbit anti-Human Polyclonal (aa1-406) Antibody
Human
ELISA, ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$412
REN / Renin 1 Mouse anti-Mouse Monoclonal (110) Antibody
Mouse
IHC
Unconjugated
200 µl/$660
REN / Renin 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
1 ml/$594; 10 ml/$4,084
REN / Renin 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$440; 1 mg/$594; 10 mg/$3,400
REN / Renin 1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µg/$498; 1 mg/$737; 10 mg/$3,983
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
REN / Renin 1 Mouse anti-Human Monoclonal (6E2-B7) Antibody
Dog, Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$403; 1 mg/$1,399
REN / Renin 1 Mouse anti-Human Monoclonal (7D3-E3) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$403; 1 mg/$1,399
REN / Renin 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
REN / Renin 1 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, IHC-P
Unconjugated
100 µl/$412
REN / Renin 1 Sheep anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
100 µg/$438; 1 mg/$589; 10 mg/$4,205
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