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RELN / Reelin

reelin

Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.

Gene Name: reelin
Synonyms: RELN, LIS2, PRO1598, Reelin, RL
Target Sequences: NM_005045 NP_005036.2 P78509

Publications (3)

1
Kainic Acid-Induced Golgi Complex Fragmentation/Dispersal Shifts the Proteolysis of Reelin in Primary Rat Neuronal Cells: An In Vitro Model of Early Stage Epilepsy. Kaneko Y, Sullivan R, Dailey T, Vale FL, Tajiri N, Borlongan CV. Molecular neurobiology. 2016 53:1874-1883. (WB) [Full Text Article] [PubMed:25790952] [PMC:PMC4577368]
2
Rare RELN variants affect Reelin-DAB1 signal transduction in autism spectrum disorder. Sandra M Sánchez-Sánchez, Juliana Magdalon, Karina Griesi-Oliveira, Guilherme L Yamamoto, Carolina Santacruz-Perez, Mariana Fogo, Maria Rita Passos-Bueno, Andrea L Sertié. Human mutation. 2018 October;39:1372-1383. [Full Text Article] [PubMed:29969175]
3
Circulating Reelin promotes inflammation and modulates disease activity in acute and long COVID-19 cases. Laurent Calvier, Aleksandra Drelich, Jason Hsu, Chien-Te Tseng, Yair Mina, Avindra Nath, Maria Z Kounnas, Joachim Herz. Frontiers in immunology. 2023 July;14:1185748. [Full Text Article] [PubMed:37441066] [PMC:PMC10333573]

☰ Filters
Antibodies (68)
ELISA Kits (14)
Proteins (10)
Custom (4)
Over-Expression Lysate (2)
Primary (68)
Recombinant (8)
Sandwich (9)
Sandwich CLIA (1)
RELN / Reelin (92)
Human (54)
Mouse (16)
Rat (23)
Chicken (1)
IHC (9)
IHC-Fr (1)
IHC-P (7)
WB (66)
ELISA (7)
ICC (10)
IP (8)
Peptide-ELISA (1)
rabbit (57)
mouse (9)
goat (1)
rat (1)
Product Group
IHCPlus (2)
IgG (15)
IgG1,k (1)
IgG2a (1)
monoclonal mc (10)
polyclonal pc (58)
96-Well Microplate (3)
96-Well Strip Plate (11)
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APC Conjugated (7)
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Cy3 Conjugated (7)
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Unconjugated (14)
aa2400-2610 (16)
aa2398-2608 (10)
aa2086-2296 (8)
aa26-190 (8)
aa3142-3460 (8)
aa3143-3461 (8)
aa164-496 (1)
aa27-861 (1)
aa27-862 (1)
No (90)
Yes (2)
Cell Culture Supernatants (1)
Cell Lysates (2)
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Serum (8)
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6His, N-terminus (2)
His (1)
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His-T7 (3)
Myc-DDK (Flag) (2)
Human (7)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (7)
HEK 293 Cells (1)
Yeast (1)
Select
RELN / Reelin Goat anti-Mouse Polyclonal (aa27-862) Antibody
Mouse
ELISA, IHC, WB
Unconjugated
100 µg/$962
Select
RELN / Reelin Mouse anti-Mouse Monoclonal (aa164-496) Antibody
Mouse, Rat, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$807
RELN / Reelin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
RELN / Reelin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$730
RELN / Reelin ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
RELN / Reelin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
388.2 kDa
20 µg/$215
RELN / Reelin Antibody - 1:100 staining human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
RELN / Reelin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
RELN / Reelin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RELN / Reelin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
RELN / Reelin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RELN / Reelin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
RELN / Reelin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RELN / Reelin Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
RELN / Reelin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RELN / Reelin Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
RELN / Reelin Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
RELN / Reelin Rabbit anti-Human Polyclonal (aa26-190) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
RELN / Reelin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$748
Select
E. coli
6His, N-terminus
29 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Select
RELN / Reelin Rat anti-Mouse Monoclonal (aa27-861) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$872
RELN / Reelin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
RELN / Reelin Antibody - Western blot of recombinant RELN / Reelin.
Select
RELN / Reelin Mouse anti-Rat Monoclonal (aa2400-2610) Antibody
Rat
ICC, IP, WB
Unconjugated
100 µl/$323; 200 µl/$371; 500 µl/$531; 1 ml/$617; 2 ml/$850; 5 ml/$1,401
Select
RELN / Reelin Rabbit anti-Human Polyclonal (aa2398-2608) (Biotin) Antibody
Human
ICC, WB
Biotin Conjugated
100 µl/$318
RELN / Reelin Antibody - Western blot of recombinant RELN / Reelin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RELN / Reelin Rabbit anti-Mouse Polyclonal (aa3143-3461) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
RELN / Reelin Antibody - Western blot of recombinant RELN / Reelin.
Select
RELN / Reelin Rabbit anti-Human Polyclonal (aa26-190) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
RELN / Reelin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$783
RELN / Reelin Protein - Recombinant Reelin By SDS-PAGE
Select
E. coli
6His, N-terminus
27.5 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
RELN / Reelin ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
RELN / Reelin Protein
Select
Yeast
His
26.9 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
Select
RELN / Reelin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$351
Viewing 1-25 of 92 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).