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May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.
Gene Name: | RNA binding motif protein 15 |
Synonyms: | RBM15, One twenty two protein, One twenty-two, OTT, RNA binding motif protein 15, One-twenty two protein 1, OTT1, RNA-binding motif protein 15 |
Target Sequences: | NM_022768 NP_073605.4 Q96T37 |
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