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RBL1 / p107
retinoblastoma-like 1 (p107)
Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor.
| Gene Name: | retinoblastoma-like 1 (p107) |
| Synonyms: | RBL1, Cellular protein 107, CP107, p107, Retinoblastoma-like 1 (p107), Retinoblastoma-like protein 1 |
| Target Sequences: | NM_002895 NP_002886.2 P28749 |
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Antibodies
(44)
Type
Primary
(44)
Target
RBL1 / p107
(44)
Reactivity
Human
(44)
Mouse
(18)
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(8)
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(7)
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(7)
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(1)
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(3)
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(6)
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(6)
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(7)
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(4)
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(7)
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(1)
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(1)
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IHC
(11)
IHC-P
(2)
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(33)
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(22)
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(2)
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(5)
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(2)
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(3)
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rabbit
(39)
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(5)
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(26)
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(2)
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(1)
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(2)
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monoclonal mc
(5)
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(39)
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(1)
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(2)
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(2)
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(2)
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(2)
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(5)
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(2)
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(5)
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(5)
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(2)
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(25)
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aa1007-1035
(7)
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(6)
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(4)
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(4)
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(2)
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(2)
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(1)
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(1)
aa1018-1068
(1)
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(1)
aa335-384
(1)
Publications
No
(44)
RBL1 / p107 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
30 µl/$255; 50 µl/$271; 100 µl/$299; 200 µl/$351
RBL1 / p107 Rabbit anti-Human Polyclonal (aa335-384) Antibody
Mouse, Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
RBL1 / p107 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$302
RBL1 / p107 Rabbit anti-Human Polyclonal (pSer975) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
RBL1 / p107 Rabbit anti-Human Polyclonal (pSer975) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
RBL1 / p107 Rabbit anti-Human Polyclonal (pSer975) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
RBL1 / p107 Rabbit anti-Human Polyclonal (pSer975) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
RBL1 / p107 Rabbit anti-Human Polyclonal (pSer975) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
RBL1 / p107 Rabbit anti-Human Polyclonal (pSer975) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
RBL1 / p107 Rabbit anti-Human Polyclonal (aa1048-1068) Antibody
Chicken, Sheep, Bovine, Rat, Pig, Horse, Bat, Rabbit, Mouse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µg/$470
RBL1 / p107 Rabbit anti-Human Polyclonal (310-390 aa) Antibody
Mouse, Human
ELISA, IF
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
RBL1 / p107 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$282; 200 µl/$350
RBL1 / p107 Rabbit anti-Human Polyclonal (310-390 aa) Antibody
Mouse, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
RBL1 / p107 Rabbit anti-Human Polyclonal (Ab-369) Antibody
Mouse, Human
ELISA, IF
Unconjugated
100 µg/$357
RBL1 / p107 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$341
RBL1 / p107 Rabbit anti-Human Polyclonal (pThr369) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
RBL1 / p107 Rabbit anti-Human Polyclonal (pThr369) Antibody
Mouse, Human
ELISA, IHC
Unconjugated
100 µg/$357
RBL1 / p107 Mouse anti-Human Monoclonal (1A5) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$335
RBL1 / p107 Rabbit anti-Human Polyclonal (aa1007-1035) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
RBL1 / p107 Rabbit anti-Human Polyclonal (aa1007-1035) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
RBL1 / p107 Rabbit anti-Human Polyclonal (aa1007-1035) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
RBL1 / p107 Rabbit anti-Human Polyclonal (aa1007-1035) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
RBL1 / p107 Rabbit anti-Human Polyclonal (aa1007-1035) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
RBL1 / p107 Rabbit anti-Human Polyclonal (aa1007-1035) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
RBL1 / p107 Mouse anti-Human Monoclonal (aa739-1014) (Carrier-free) (OTI4A10) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
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product results
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