RARRES2 / Chemerin

retinoic acid receptor responder (tazarotene induced) 2

Adipocyte-secreted protein (adipokine) that regulates adipogenesis, metabolism and inflammation through activation of the chemokine-like receptor 1 (CMKLR1). Its other ligands include G protein-coupled receptor 1 (GPR1) and chemokine receptor-like 2 (CCRL2). Positively regulates adipocyte differentiation, modulates the expression of adipocyte genes involved in lipid and glucose metabolism and might play a role in angiogenesis, a process essential for the expansion of white adipose tissue. Also acts as a proinflammatory adipokine, causing an increase in secretion of proinflammatory and prodiabetic adipokines, which further impair adipose tissue metabolic function and have negative systemic effects including impaired insulin sensitivity, altered glucose and lipid metabolism, and a decrease in vascular function in other tissues. Can have both pro- and anti-inflammatory properties depending on the modality of enzymatic cleavage by different classes of proteases. Acts as a chemotactic factor for leukocyte populations expressing CMKLR1, particularly immature plasmacytoid dendritic cells, but also immature myeloid DCs, macrophages and natural killer cells. Exerts an anti-inflammatory role by preventing TNF/TNFA-induced VCAM1 expression and monocytes adhesion in vascular endothelial cells. The effect is mediated via inhibiting activation of NF-kappa-B and CRK/p38 through stimulation of AKT1/NOS3 signaling and nitric oxide production. Its dual role in inflammation and metabolism might provide a link between chronic inflammation and obesity, as well as obesity-related disorders such as type 2 diabetes and cardiovascular disease. Exhibits an antimicrobial function in the skin.

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Products

ELISA Kits (29)

Type

Competitive EIA (1)

Custom (1)

Development Kit (2)

Sandwich (23)

Sandwich CLIA (2)

Target

RARRES2 / Chemerin (29)

Reactivity

Human (11)

Mouse (11)

Rat (4)

Bovine (1)

Pig (2)

Product Group

DevKit DuoPlus (2)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (8)

96-Well Strip Plate (17)

Antibody Pair and Standard (2)

Publications

No (29)

Sample Type

Cell Culture Supernatants (9)

Cell Lysates (4)

Plasma (28)

Serum (28)

Tissue Homogenates (12)

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Rat RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F6900

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$715

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Human RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F20979

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F4641

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$764

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Mouse RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F23741

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

46.875 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Human RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F2980

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$699

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Mouse RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F2981

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$699

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Mouse RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F10348

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$744

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Mouse RARRES2 / Chemerin (Custom ELISA) ELISA Kit - LS-F376

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$823

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Human RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F55

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.205 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$760

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Pig RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F74244

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Pig

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$779

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DevKit DuoPlus Mouse RARRES2 / Chemerin ELISA Development Kit - LS-F71330

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Mouse

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$947; 1000 Wells/$1,354

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DevKit DuoPlus Human RARRES2 / Chemerin ELISA Development Kit - LS-F71596

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$1,182; 1000 Wells/$1,747

Select

Human RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F54702

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$968

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Human RARRES2 / Chemerin (CLIA) ELISA Kit - LS-F29531

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Human RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F31466

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

780 - 50000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$624

Select

Mouse RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F31502

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

780 - 50000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$582

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Mouse RARRES2 / Chemerin (CLIA) ELISA Kit - LS-F30416

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

15.625 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Rat RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F40450

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F36365

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F36366

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

46.875 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rat RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F36367

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Pig RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F36370

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F28677

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

50 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Rat RARRES2 / Chemerin (Sandwich ELISA) ELISA Kit - LS-F27374

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

50 - 1000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Human RARRES2 / Chemerin (Competitive EIA) ELISA Kit - LS-F27654

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

100 - 2500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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