RARA / RAR Alpha

retinoic acid receptor, alpha

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (By similarity). Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing KMT2E/MLL5. Mediates retinoic acid-induced granulopoiesis.

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Antibodies (86)

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RARA / RAR Alpha (118)

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IHC-plus™ RARA / RAR Alpha Antibody (clone 2C9-1F8) LS-B5524

(4.0) Rating

Antibody:

RARA / RAR Alpha Mouse anti-Human Monoclonal (2C9-1F8) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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RARA / RAR Alpha Antibody (aa52-299, clone OTI2C3) LS-C339986

Antibody:

RARA / RAR Alpha Mouse anti-Human Monoclonal (aa52-299) (OTI2C3) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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RARA / RAR Alpha Antibody (aa52-299, clone OTI2C3, Carrier-free) LS-C798321

Antibody:

RARA / RAR Alpha Mouse anti-Human Monoclonal (aa52-299) (Carrier-free) (OTI2C3) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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Human RARA / RAR Alpha Protein (Recombinant His) - LS-G3542

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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IHC-plus™ RARA / RAR Alpha Antibody (clone 2D2) LS-B5525

(4.0) Rating

Antibody:

RARA / RAR Alpha Mouse anti-Human Monoclonal (2D2) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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RARA / RAR Alpha Antibody (aa322-349) LS-C162444

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal (aa322-349) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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RARA / RAR Alpha Antibody (C-Terminus) LS-C137055

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$332

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RARA / RAR Alpha Antibody LS-C667974

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$266; 50 µl/$286; 100 µl/$321; 200 µl/$386

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RARA / RAR Alpha Antibody LS-C330934

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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RARA / RAR Alpha Antibody (aa322-349) LS-C324532

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal (aa322-349) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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RARA / RAR Alpha Antibody (aa322-349, Biotin) LS-C284981

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal (aa322-349) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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RARA / RAR Alpha Antibody (aa322-349, FITC) LS-C284984

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal (aa322-349) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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RARA / RAR Alpha Antibody (aa322-349, APC) LS-C284982

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal (aa322-349) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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RARA / RAR Alpha Antibody (aa322-349, Azide-free, HRP) LS-C284983

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal (aa322-349) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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RARA / RAR Alpha Antibody (aa322-349, PE) LS-C284985

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal (aa322-349) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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RARA / RAR Alpha Antibody LS-C805967

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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RARA / RAR Alpha Antibody LS-C755156

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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RARA / RAR Alpha Antibody (phospho-Ser77) LS-C800209

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal (pSer77) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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Mouse/Human/Rat RARA / RAR Alpha (DNA-Binding ELISA) ELISA Kit - LS-F809

Type:

DNA Binding

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$694

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RARA / RAR Alpha Antibody (C-Terminus) LS-C55366

Antibody:

RARA / RAR Alpha Goat anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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RARA / RAR Alpha Antibody (phospho-Ser77) LS-C199534

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal (pSer77) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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RARA / RAR Alpha Antibody (20-100 aa) LS-C381403

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal (20-100 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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RARA / RAR Alpha Antibody (20-100 aa) LS-C385785

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal (20-100 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

RARA / RAR Alpha Antibody (phospho-Ser77) LS-C827076

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal (pSer77) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

RARA / RAR Alpha Antibody (phospho-Ser77) LS-C825491

Antibody:

RARA / RAR Alpha Rabbit anti-Human Polyclonal (pSer77) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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