RAP1GAP

RAP1 GTPase activating protein

RAP1GAP is a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins.

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Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

RAP1GAP (6)

Publications

No (6)

Tag

GST (1)

Myc-DDK (Flag) (5)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (1)

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RAP1GAP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117687

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

73.2 kDa

Price:

100 µg/$494

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RAP1GAP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126782

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

75 kDa

Price:

100 µg/$710

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Human RAP1GAP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66805

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

73.2 kDa

Price:

20 µg/$1,107

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Human RAP1GAP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78526

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

75 kDa

Price:

20 µg/$215

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Human RAP1GAP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78527

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

73.2 kDa

Price:

20 µg/$150

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Human RAP1GAP Protein (Recombinant GST) (Full Length) - LS-G30111

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

98.67 kDa

Price:

2 µg/$439

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