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RAB7B

RAB7B, member RAS oncogene family

Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.

Gene Name: RAB7B, member RAS oncogene family
Synonyms: RAB7B, RAB7, Ras-related protein Rab-7, Ras-related protein Rab-7b
Target Sequences: Q96AH8 Q96AH8

☰ Filters
Products
Proteins (8)
Over-Expression Lysate (4)
Recombinant (4)
RAB7B (8)
No (8)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (6)
Human (6)
293T Cells (2)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (1)
RAB7B Protein - Purified recombinant protein RAB7B was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
22.3 kDa
20 µg/$1,107
RAB7B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
22.3 kDa
100 µg/$494
RAB7B Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
RAB7B Protein - Purified recombinant protein RAB7B was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
22.3 kDa
20 µg/$1,107
RAB7B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
22.3 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
22.3 kDa
20 µg/$150
RAB7B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
22.3 kDa
100 µg/$494
RAB7B Protein - 12.5% SDS-PAGE of human RAB7B stained with Coomassie Blue
Select
Wheat Germ Extract
GST
47.63 kDa
10 µg/$479; 25 µg/$670
Viewing 1-8 of 8 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).