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RAB3GAP2 / p150
RAB3 GTPase activating protein subunit 2 (non-catalytic)
Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
| Gene Name: | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| Synonyms: | RAB3GAP2, DKFZP434D245, p150, KIAA0839, Rab3-GAP p150, RAB3-GAP150, RAB3GAP150, RGAP-iso, WARBM2, RP11-568G11.1, Rab3-GAP regulatory subunit |
| Target Sequences: | NM_012414 NP_036546.2 Q9H2M9 |
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