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Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
Gene Name: | RAB3 GTPase activating protein subunit 1 (catalytic) |
Synonyms: | RAB3GAP1, KIAA0066, p130, RAB3GAP, RAB3GAP130, WARBM1, Rab3-GAP p130, Rab3-GAP |
Target Sequences: | D31886 BAA06684.1 Q15042 |
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