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The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion By similarity. Required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins.
Gene Name: | RAB30, Member RAS Oncogene Family |
Family/Subfamily: | Ras GTPase superfamily IPR001806 , RAS oncogene |
Synonyms: | RAB30, Ras-related protein Rab-30 |
Target Sequences: | NM_014488 NP_055303.2 Q15771 |
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