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R1 / RRM1

ribonucleotide reductase M1

R1 / RRM1 is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Gene Name: ribonucleotide reductase M1
Synonyms: RRM1, R1, Ribonucleotide reductase M1, RR1, RIR1
Target Sequences: NM_001033 NP_001024.1 P23921

☰ Filters
Antibodies (74)
Proteins (8)
ELISA Kits (5)
Custom (2)
Over-Expression Lysate (2)
Primary (74)
Recombinant (6)
Sandwich (3)
R1 / RRM1 (87)
Human (76)
Mouse (19)
Rat (9)
Bat (6)
Bovine (6)
Chicken (3)
Chimpanzee (6)
Dog (6)
Gibbon (6)
Guinea pig (6)
Hamster (3)
Horse (6)
Monkey (6)
Orangutan (6)
Pig (6)
Rabbit (6)
Xenopus (3)
Zebrafish (7)
IHC (25)
IHC-P (9)
WB (66)
Flo (1)
ELISA (21)
ICC (2)
IF (9)
IP (4)
Peptide-ELISA (2)
rabbit (47)
mouse (27)
Ig (1)
IgG (34)
IgG1 (22)
IgG2a (2)
IgG2a,k (1)
monoclonal mc (27)
polyclonal pc (47)
3D6H5 (1)
4E4 (1)
OTI12B9 (2)
OTI13E4 (2)
OTI16A8 (2)
OTI17C3 (2)
OTI1F9 (2)
OTI2D10 (2)
OTI3G5 (2)
OTI5G5 (2)
OTI6G8 (2)
OTI9A2 (2)
UMAB165 (2)
96-Well Strip Plate (5)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (6)
Carrier-free (11)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (2)
Unconjugated (50)
aa541-792 (20)
aa1-213 (8)
aa71-100 (7)
aa1-792 (4)
aa257-306 (4)
aa723-772 (4)
aa742-792 (1)
aa86-120 (1)
No (87)
Plasma (2)
Serum (2)
Tissue Homogenates (3)
GST, N-terminus (2)
His (1)
His-S (1)
His-SUMO (1)
Myc-DDK (Flag) (3)
Human (7)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Yeast (1)
R1 / RRM1 Protein - Purified recombinant protein RRM1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
89.9 kDa
20 µg/$1,107
R1 / RRM1 Antibody - Lane A: Marker. Lane B: HepG2 cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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R1 / RRM1 Rabbit anti-Human Polyclonal (aa723-772) Antibody
Human
WB
Unconjugated
100 µl/$397
R1 / RRM1 Antibody - IHC of paraffin-embedded Human breast tissue using anti-RRM1 mouse monoclonal antibody.
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R1 / RRM1 Mouse anti-Human Monoclonal (OTI5G5) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
R1 / RRM1 Antibody - IHC of paraffin-embedded Human breast tissue using anti-RRM1 mouse monoclonal antibody.
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R1 / RRM1 Mouse anti-Human Monoclonal (aa541-792) (Carrier-free) (OTI5G5) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
R1 / RRM1 Antibody - Immunohistochemistry of paraffin-embedded human prostate using RRM1 antibodyat dilution of 1:200 (40x lens).
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R1 / RRM1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, IP, WB
Unconjugated
20 µl/$275; 100 µl/$389
R1 / RRM1 Antibody - Immunohistochemical analysis of RRM1 staining in human prostate formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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R1 / RRM1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
R1 / RRM1 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-RRM1 mouse monoclonal antibody.  heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
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R1 / RRM1 Mouse anti-Human Monoclonal (aa541-792) (UMAB165) Antibody
Human
IF, IHC, WB
Unconjugated
100 µl/$493
R1 / RRM1 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-RRM1 mouse monoclonal antibody.  heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
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R1 / RRM1 Mouse anti-Human Monoclonal (aa541-792) (Carrier-free) (UMAB165) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$539
R1 / RRM1 Antibody - Western blot of R1 / RRM1 antibody.
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R1 / RRM1 Rabbit anti-Human Polyclonal (aa1-213) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
R1 / RRM1 Antibody - 1:100 staining human lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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R1 / RRM1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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R1 / RRM1 Mouse anti-Human Monoclonal Antibody
Human
Flo, ICC, IF
Unconjugated
100 µl/$412
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R1 / RRM1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$466
Select
E. coli
His-SUMO
106.01 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Select
Yeast
His
92.07 kD
1 mg/$1,607; 100 µg/$469; 20 µg/$349
R1 / RRM1 Antibody - Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-RRM1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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R1 / RRM1 Mouse anti-Human Monoclonal (aa541-792) (OTI6G8) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
R1 / RRM1 Antibody - Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-RRM1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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R1 / RRM1 Mouse anti-Human Monoclonal (aa541-792) (Carrier-free) (OTI6G8) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
R1 / RRM1 Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-RRM1 Mouse monoclonal antibody. (heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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R1 / RRM1 Mouse anti-Human Monoclonal (aa541-792) (OTI16A8) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
R1 / RRM1 Antibody - Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-RRM1 Mouse monoclonal antibody.  heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
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R1 / RRM1 Mouse anti-Human Monoclonal (aa541-792) (Carrier-free) (OTI16A8) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
Select
R1 / RRM1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$406
Select
R1 / RRM1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$371
Select
R1 / RRM1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$341
R1 / RRM1 Antibody - Immunofluorescence analysis of U2OS cells using RRM1 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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R1 / RRM1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IP, WB
Unconjugated
20 µl/$275; 100 µl/$389
Select
R1 / RRM1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
R1 / RRM1 Antibody - Immunohistochemistry of paraffin-embedded human lung cancer using product in 30ug/ml dilute concentrations.
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R1 / RRM1 Mouse anti-Human Monoclonal (3D6H5) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$316; 100 µg/$386
R1 / RRM1 Antibody - IHC of paraffin-embedded Human colon tissue using anti-RRM1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
Select
R1 / RRM1 Mouse anti-Human Monoclonal (aa541-792) (OTI1F9) Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$434
Viewing 1-25 of 87 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).