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QPRT

quinolinate phosphoribosyltransferase

QPRT is a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.

Gene Name: quinolinate phosphoribosyltransferase
Synonyms: QPRT, QPRTase, QAPRTase
Target Sequences: NM_014298 NP_055113.2 Q15274

Publications (2)

1
Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease. Jones SP, Franco NF, Varney B, Sundaram G, Brown DA, de Bie J, Lim CK, Guillemin GJ, Brew BJ. PloS one. 2015 10:e0131389. (WB; Human) [Full Text Article] [PubMed:26114426] [PMC:PMC4482723] Related Antibodies: LS-C115527.
2
Berberine-induced TFEB deacetylation by SIRT1 promotes autophagy in peritoneal macrophages. Yinghong Zheng, Jiayuan Kou, Pengyu Wang, Ting Ye, Zitong Wang, Ziyu Gao, Lin Cong, Manman Li, Bowen Dong, Wei Yang, Quanfeng Li, Hong Li, Rui Wang, Liming Yang. Aging. 2021 Feb;13:7096-7119. [Full Text Article] [PubMed:33639613] [PMC:PMC7993719]

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Antibodies (31)
Primary (31)
QPRT (31)
Human (29)
Mouse (1)
Rat (1)
IHC (15)
IHC-P (8)
WB (27)
Flo (15)
ELISA (13)
ICC (1)
IF (10)
rabbit (13)
mouse (18)
Product Group
IHCPlus (2)
IgG (12)
IgG1 (12)
IgG1,k (1)
IgG2a (2)
IgG2a,k (1)
IgG2b (2)
monoclonal mc (18)
polyclonal pc (13)
5D11 (1)
AT24C4 (1)
OTI1C10 (2)
OTI2H4 (2)
OTI3B3 (2)
OTI4B3 (2)
OTI4B4 (2)
OTI4E5 (2)
OTI4E6 (2)
OTI7A8 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
Carrier-free (8)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (23)
aa206-234 (7)
No (30)
Yes (1)
QPRT Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-QPRT mouse monoclonal antibody.
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QPRT Mouse anti-Human Monoclonal (OTI7A8) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
QPRT Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-QPRT mouse monoclonal antibody.
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QPRT Mouse anti-Human Monoclonal (Carrier-free) (OTI7A8) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
QPRT Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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QPRT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
QPRT Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
QPRT Mouse anti-Human Monoclonal (AT24C4) Antibody
Human
ELISA, ICC, IF, IHC-P, WB
Unconjugated
50 µl/$460
QPRT Antibody - IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-QPRT mouse monoclonal antibody.
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QPRT Mouse anti-Human Monoclonal (OTI1C10) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
QPRT Antibody - IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-QPRT mouse monoclonal antibody.
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QPRT Mouse anti-Human Monoclonal (Carrier-free) (OTI1C10) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
QPRT Antibody - Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-QPRT mouse monoclonal antibody.
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QPRT Mouse anti-Human Monoclonal (OTI4E6) Antibody
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
QPRT Antibody - Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-QPRT mouse monoclonal antibody.
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QPRT Mouse anti-Human Monoclonal (Carrier-free) (OTI4E6) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
QPRT Antibody - Immunoperoxidase of monoclonal antibody to QPRT on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml].
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QPRT Mouse anti-Human Monoclonal (5D11) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$423
QPRT Antibody - Anti-QPRT mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY QPRT.
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QPRT Mouse anti-Human Monoclonal (OTI4E5) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
QPRT Antibody - Anti-QPRT mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY QPRT.
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QPRT Mouse anti-Human Monoclonal (Carrier-free) (OTI4E5) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
QPRT Antibody - Immunohistochemistry Dilution at 1:300 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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QPRT Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
QPRT Antibody - Anti-QPRT mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY QPRT.
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QPRT Mouse anti-Human Monoclonal (OTI3B3) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
QPRT Antibody - Anti-QPRT mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY QPRT.
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QPRT Mouse anti-Human Monoclonal (Carrier-free) (OTI3B3) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
Select
QPRT Rabbit anti-Human Polyclonal (aa206-234) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
QPRT Rabbit anti-Human Polyclonal (aa206-234) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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QPRT Rabbit anti-Human Polyclonal (aa206-234) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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QPRT Rabbit anti-Human Polyclonal (aa206-234) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
QPRT Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY QPRT (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-QPRT.
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QPRT Mouse anti-Human Monoclonal (OTI4B3) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
QPRT Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY QPRT (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-QPRT.
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QPRT Mouse anti-Human Monoclonal (Carrier-free) (OTI4B3) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
QPRT Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY QPRT (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-QPRT.
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QPRT Mouse anti-Human Monoclonal (OTI4B4) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
QPRT Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY QPRT (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-QPRT.
Select
QPRT Mouse anti-Human Monoclonal (Carrier-free) (OTI4B4) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
QPRT Antibody - Anti-QPRT mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY QPRT.
Select
QPRT Mouse anti-Human Monoclonal (OTI2H4) Antibody
IF, WB
Unconjugated
100 µl/$434
QPRT Antibody - Anti-QPRT mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY QPRT.
Select
QPRT Mouse anti-Human Monoclonal (Carrier-free) (OTI2H4) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
QPRT Antibody - QPRT Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human tonsil tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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QPRT Rabbit anti-Human Polyclonal (aa206-234) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Viewing 1-25 of 31 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).