PYGL

phosphorylase, glycogen, liver

PYGL is a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues. In glycogen storage disease type VI, also known as Hers disease, mutations in liver glycogen phosphorylase inhibit the conversion of glycogen to glucose and results in moderate hypoglycemia, mild ketosis, growth retardation and hepatomegaly. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Products

Antibodies (66)

ELISA Kits (20)

Proteins (12)

Type

Competitive EIA (3)

Custom (3)

Over-Expression Lysate (2)

Primary (66)

Recombinant (10)

Sandwich (11)

Sandwich CLIA (3)

Target

PYGL (98)

Reactivity

Human (54)

Mouse (29)

Rat (45)

Dog (1)

Monkey (2)

Application

IHC (13)

IHC-P (9)

WB (63)

ELISA (7)

ICC (6)

IF (6)

IP (5)

Peptide-ELISA (2)

Host

rabbit (58)

mouse (8)

Product Group

IHCPlus (3)

Isotype

IgG (12)

IgG2a,k (8)

Clonality

monoclonal mc (8)

polyclonal pc (58)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (3)

96-Well Strip Plate (15)

APC (6)

APC Conjugated (6)

Biotin Conjugated (8)

Cy3 Conjugated (6)

Cy7 Conjugated (6)

FITC Conjugated (8)

HRP Conjugated (7)

PE Conjugated (6)

Unconjugated (19)

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Epitope

aa73-267 (10)

aa341-509 (8)

aa370-538 (8)

aa603-750 (8)

aa633-820 (8)

C-Terminus (1)

Internal (1)

aa797-847 (1)

aa809-843 (1)

Publications

No (98)

Sample Type

Plasma (15)

Serum (15)

Tissue Homogenates (6)

Tag

GST (2)

His (7)

Myc-DDK (Flag) (3)

Species

Human (8)

Rat (3)

Source

293T Cells (1)

E. coli (7)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (3)

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IHC-plus™ PYGL Antibody (Internal) LS-A2283

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(4.0) Rating

Antibody:

PYGL Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Dog, Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$395

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Human PYGL (Sandwich ELISA) ELISA Kit - LS-F4194

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$764

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IHC-plus™ PYGL Antibody (C-Terminus) LS-A1488

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(4.0) Rating

Antibody:

PYGL Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$395

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Human PYGL Protein (Recombinant GST) (Full Length) - LS-G21104

Source:

E. coli

Tag:

GST

Molecular Weight:

124.2 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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PYGL Antibody LS-C482685

Antibody:

PYGL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$266; 50 µl/$286; 100 µl/$321; 200 µl/$386

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PYGL Antibody LS-C754812

Antibody:

PYGL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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PYGL Antibody LS-C754811

Antibody:

PYGL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$351

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IHC-plus™ PYGL Antibody LS-B12977

(4.0) Rating

Antibody:

PYGL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$375

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PYGL Antibody (HRP) LS-C317223

Antibody:

PYGL Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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PYGL Antibody (Biotin) LS-C317222

Antibody:

PYGL Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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PYGL Antibody (FITC) LS-C318841

Antibody:

PYGL Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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PYGL Antibody LS-C334896

Antibody:

PYGL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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Human PYGL (Sandwich ELISA) ELISA Kit - LS-F33031

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human PYGL (CLIA) ELISA Kit - LS-F29845

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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PYGL Antibody LS-C401957

Antibody:

PYGL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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PYGL Antibody (aa809-843) LS-C392999

Antibody:

PYGL Rabbit anti-Human Polyclonal (aa809-843) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

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PYGL Antibody (aa370-538) LS-C294286

Antibody:

PYGL Rabbit anti-Human Polyclonal (aa370-538) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141

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PYGL Antibody LS-C802640

Antibody:

PYGL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$282; 200 µl/$350

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PYGL Antibody LS-C817068

Antibody:

PYGL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P

Format:

Unconjugated

Price:

100 µl/$302

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PYGL Antibody LS-C770084

Antibody:

PYGL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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PYGL Antibody (aa341-509) LS-C294284

Antibody:

PYGL Rabbit anti-Rat Polyclonal (aa341-509) Antibody

Reactivity:

Rat, Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206

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PYGL Antibody (aa797-847) LS-C291000

Antibody:

PYGL Rabbit anti-Human Polyclonal (aa797-847) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µg/$295; 100 µg/$514

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PYGL Antibody (aa73-267, Biotin) LS-C419690

Antibody:

PYGL Rabbit anti-Rat Polyclonal (aa73-267) (Biotin) Antibody

Reactivity:

Rat

Applications:

ICC, WB

Format:

Biotin Conjugated

Price:

100 µl/$316

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PYGL Antibody (aa73-267, FITC) LS-C419691

Antibody:

PYGL Rabbit anti-Rat Polyclonal (aa73-267) (FITC) Antibody

Reactivity:

Rat

Applications:

ICC, WB

Format:

FITC Conjugated

Price:

100 µl/$325

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PYGL Antibody (aa633-820) LS-C294283

Antibody:

PYGL Rabbit anti-Human Polyclonal (aa633-820) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141

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