Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Location


Corporate Headquarters

Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States

Telephone Numbers



Customer Service: (800) 227-6666 / (650) 697-3600


Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

PVRL4 / Nectin 4

poliovirus receptor-related 4

PVRL4 / Nectin 4 is a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

Gene Name: poliovirus receptor-related 4
Synonyms: PVRL4, EDSS1, Nectin 4, Ig superfamily receptor LNIR, Poliovirus receptor-like 4, LNIR, Nectin-4, Poliovirus receptor-related 4
Target Sequences: NM_030916 NP_112178.2 Q96NY8

Publications (1)

1
Adherens junction protein nectin-4 is the epithelial receptor for measles virus. Mhlebach MD, Mateo M, Sinn PL, Prfer S, Uhlig KM, Leonard VH, Navaratnarajah CK, Frenzke M, Wong XX, Sawatsky B, Ramachandran S, McCray PB, Cichutek K, von Messling V, Lopez M, Cattaneo R. Nature. 2011 480:530-3. (Flo; Human) [Full Text Article] [PubMed:22048310] [PMC:PMC3245798] Related Antibodies: LS-C37483.

☰ Filters
Products
Proteins (11)
Over-Expression Lysate (2)
Recombinant (9)
PVRL4 / Nectin 4 (11)
No (11)
6His, C-terminus (3)
Fc, C-terminus (1)
GST (1)
GST, N-terminus (1)
His (2)
Myc-DDK (Flag) (3)
Human (8)
Mouse (1)
Poliovirus (1)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Human (1)
Human Cells (1)
Mammalian Cells (2)
Wheat Germ Extract (2)
Yeast (1)
Purified (1)
Low endotoxin level (4)
Biologically active (1)
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
35.3kD
10 µg/$277; 50 µg/$395; 500 µg/$1,203
PVRL4 / Nectin 4 Protein - 12.5% SDS-PAGE of human PVRL4 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
81.9 kDa
2 µg/$439
PVRL4 / Nectin 4 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PVRL4 / Nectin 4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
55.3 kDa
20 µg/$150
PVRL4 / Nectin 4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
55.3 kDa
100 µg/$494
PVRL4 / Nectin 4 Protein - Purified recombinant protein NECTIN4 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
55.3 kDa
20 µg/$1,107
PVRL4 / Nectin 4 Protein - Recombinant Mouse Nectin-4 (C-Fc)
Select
Human
Fc, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
61.4kDa
10 µg/$286; 50 µg/$362
PVRL4 / Nectin 4 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
35.3 kDa
50 µg/$453; 10 µg/$298; 1 mg/$2,064; 500 µg/$1,470
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
35.3 kDa
10 µg/$277; 50 µg/$389
PVRL4 / Nectin 4 Protein
Select
Yeast
His
36.1 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
PVRL4 / Nectin 4 Protein - Recombinant Poliovirus Receptor Related Protein 4 By SDS-PAGE
Select
E. coli
His
34.5 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,441
Viewing 1-11 of 11 product results


Filtered By:
Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).