PVRL3 / Nectin-3

poliovirus receptor-related 3

Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.

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Products

Proteins (9)

Type

Over-Expression Lysate (2)

Recombinant (7)

Target

PVRL3 / Nectin-3 (9)

Publications

No (9)

Tag

6His, C-terminus (2)

GST (1)

GST, N-terminus (1)

His (1)

His-T7 (2)

Myc-DDK (Flag) (2)

Species

Human (7)

Mouse (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Human Cells (2)

Mammalian Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (3)

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Mouse PVRL3 / Nectin-3 Protein (Recombinant His-T7) (aa90-293) - LS-G13859

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.1 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human PVRL3 / Nectin-3 Protein (Recombinant GST) (Full Length) - LS-G33040

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

66.1 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PVRL3 / Nectin-3 Protein (Recombinant 6His, C-terminus) (Gly58-Cys366) - LS-G39099

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

34.96kD

Price:

10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157

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Human PVRL3 / Nectin-3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82853

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.8 kDa

Price:

20 µg/$215

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Human PVRL3 / Nectin-3 Protein (Recombinant His) (Met1-Asp400) - LS-G98648

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

39.3 kDa

Price:

100 µg/$721

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PVRL3 / Nectin-3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101325

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.8 kDa

Price:

100 µg/$710

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Human PVRL3 / Nectin-3 Protein (Recombinant GST, N-terminus) (aa59-166) - LS-G62115

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PVRL3 / Nectin-3 Protein (Recombinant 6His, C-terminus) (Gly58-Cys366) - LS-G138968

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

35.0 kDa

Price:

10 µg/$269; 50 µg/$368

Select

Human PVRL3 / Nectin-3 Protein (Recombinant His-T7) (aa171-377) - LS-G13858

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.6 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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