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6737 Mowry Ave
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PVRL3 / Nectin-3

poliovirus receptor-related 3

Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.

Gene Name: poliovirus receptor-related 3
Synonyms: PVRL3, CDW113, DKFZP566B0846, Nectin 3, PPR3, Poliovirus receptor-related 3, CD113, CD113 antigen, NECTIN-3, PVRR3
Target Sequences: NM_015480 NP_056295.1 Q9NQS3

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Products
Antibodies (54)
Primary (54)
PVRL3 / Nectin-3 (54)
Human (41)
Mouse (27)
Rat (16)
Bat (6)
Bovine (6)
Chimpanzee (6)
Dog (6)
Gibbon (6)
Guinea pig (3)
Horse (3)
Monkey (3)
Pig (6)
Rabbit (6)
IHC (10)
IHC-Fr (5)
IHC-P (3)
WB (44)
Flo (6)
ELISA (21)
Func (3)
ICC (1)
IF (3)
IP (6)
Peptide-ELISA (3)
rabbit (44)
mouse (4)
goat (1)
rat (5)
Product Group
IHCPlus (1)
IgG (21)
IgG1 (1)
IgG2a (5)
IgG2a,k (1)
monoclonal mc (9)
polyclonal pc (45)
103-A1 (4)
13A62 (1)
1D1 (1)
6D5B2 (1)
APC (2)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (6)
Concentrated (1)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (7)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (26)
aa171-377 (8)
aa90-293 (8)
aa507-536 (7)
aa143-192 (4)
aa467-516 (4)
Extracellular Domain (2)
aa50-400 (2)
160-240 aa, Internal (1)
311-360 aa, Internal (1)
aa166-215 (1)
aa184-233 (1)
aa56-400 (1)
No (54)
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PVRL3 / Nectin-3 Rat anti-Mouse Monoclonal (Extracellular Domain) (103-A1) Antibody
Mouse
ELISA, Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$1,001
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PVRL3 / Nectin-3 Rat anti-Mouse Monoclonal (aa50-400) (FITC) (103-A1) Antibody
Mouse
Flo, Func, IF, IHC, IHC-Fr, IP
FITC Conjugated
100 µg/$807
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PVRL3 / Nectin-3 Rat anti-Mouse Monoclonal (Concentrated) (103-A1) Antibody
Mouse
Flo, IHC, IHC-Fr, IP, WB
Unconjugated, Concentrated
1 ml/$786
PVRL3 / Nectin-3 Antibody - Western blot analysis using CD113 mAb against HEK293 (1) and CD113 (AA: extra 282-404)-hIgGFc transfected HEK293 (2) cell lysate.
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PVRL3 / Nectin-3 Mouse anti-Human Monoclonal (6D5B2) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
PVRL3 / Nectin-3 Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa467-516) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
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PVRL3 / Nectin-3 Rat anti-Mouse Monoclonal (Extracellular Domain) (103-A1) Antibody
Mouse
Flo, Func, IF, IHC, IHC-Fr, IP
Unconjugated
100 µg/$652
PVRL3 / Nectin-3 Antibody - PVRL3 / Nectin 3 antibody Western blot of HT1080 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa143-192) Antibody
Human
WB
Unconjugated
100 µl/$424
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PVRL3 / Nectin-3 Rat anti-Mouse Monoclonal (aa50-400) (FITC) (13A62) Antibody
Mouse
ELISA, Flo, Func, ICC, IHC, IHC-Fr, IP
FITC Conjugated
100 µg/$910
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PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
PVRL3 / Nectin-3 Antibody - Staining A549 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PVRL3 / Nectin-3 Antibody - Immunohistochemistry of paraffin-embedded human prostata cancer at dilution 1:100
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PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
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PVRL3 / Nectin-3 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$412
PVRL3 / Nectin-3 Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer using PVRL3 Polyclonal Antibody at dilution of 1:40.
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PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PVRL3 / Nectin-3 Antibody - Detection limit for recombinant GST tagged PVRL3 is 0.3 ng/ml as a capture antibody.
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PVRL3 / Nectin-3 Mouse anti-Human Monoclonal (1D1) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Select
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$412
Select
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa507-536) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa507-536) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa507-536) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
PVRL3 / Nectin-3 Antibody - Western blot of Nectin 3 antibody
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PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (311-360 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PVRL3 / Nectin-3 Antibody - Western blot of Nectin 3 antibody
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PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (160-240 aa, Internal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PVRL3 / Nectin-3 Antibody - Western blot analysis of lysate from HeLa cells, using PVRL3 Antibody.
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PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PVRL3 / Nectin-3 Antibody - Western blot analysis of extracts from A549 cells, using PVRL3 antibody.
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PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
PVRL3 / Nectin-3 Antibody - Western blot of recombinant PVRL3 / Nectin-3.
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PVRL3 / Nectin-3 Rabbit anti-Mouse Polyclonal (aa90-293) Antibody
Mouse, Rat
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
PVRL3 / Nectin-3 Antibody - Western blot analysis of lysates from A549 cells, using PVRL3 Antibody. The lane on the right is blocked with the synthesized peptide.
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PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa184-233) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PVRL3 / Nectin-3 Antibody - Western blot analysis of the lysates from HUVECcells using PVRL3 antibody.
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PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa166-215) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).