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Infectious Disease
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Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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PVRL3 / Nectin-3
poliovirus receptor-related 3
Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
| Gene Name: | poliovirus receptor-related 3 |
| Synonyms: | PVRL3, CDW113, DKFZP566B0846, Nectin 3, PPR3, Poliovirus receptor-related 3, CD113, CD113 antigen, NECTIN-3, PVRR3 |
| Target Sequences: | NM_015480 NP_056295.1 Q9NQS3 |
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Products
Antibodies
(54)
Proteins
(9)
ELISA Kits
(4)
Type
Custom
(3)
Over-Expression Lysate
(2)
Primary
(54)
Recombinant
(7)
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(1)
Target
PVRL3 / Nectin-3
(67)
Reactivity
Human
(44)
Mouse
(28)
Rat
(16)
Bat
(6)
Bovine
(6)
Chimpanzee
(6)
Dog
(6)
Gibbon
(6)
Guinea pig
(3)
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(3)
Monkey
(3)
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(6)
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(6)
Application
IHC
(10)
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(5)
IHC-P
(3)
WB
(44)
Flo
(6)
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(21)
Func
(3)
ICC
(1)
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(3)
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(6)
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(3)
Host
rabbit
(44)
mouse
(4)
goat
(1)
rat
(5)
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IHCPlus
(1)
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IgG
(21)
IgG1
(1)
IgG2a
(5)
IgG2a,k
(1)
Clonality
monoclonal mc
(9)
polyclonal pc
(45)
Clone
103-A1
(4)
13A62
(1)
1D1
(1)
6D5B2
(1)
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(1)
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(2)
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(2)
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(3)
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(1)
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(6)
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(1)
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(2)
Cy7 Conjugated
(2)
FITC Conjugated
(7)
HRP Conjugated
(5)
PE Conjugated
(3)
Unconjugated
(26)
Epitope
aa171-377
(8)
aa90-293
(8)
aa507-536
(7)
aa143-192
(4)
aa467-516
(4)
Extracellular Domain
(2)
aa50-400
(2)
160-240 aa, Internal
(1)
311-360 aa, Internal
(1)
aa166-215
(1)
aa184-233
(1)
aa56-400
(1)
Publications
No
(67)
Sample Type
Cell Culture Supernatants
(1)
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(1)
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(1)
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(1)
Tag
6His, C-terminus
(2)
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(1)
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(1)
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(1)
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(2)
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(2)
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(7)
Mouse
(1)
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293T Cells
(1)
E. coli
(2)
HEK 293 Cells
(1)
Human Cells
(2)
Mammalian Cells
(1)
Wheat Germ Extract
(2)
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Purified
(2)
Low Endotoxin Level
Low endotoxin level
(3)
PVRL3 / Nectin-3 Rat anti-Mouse Monoclonal (Extracellular Domain) (103-A1) Antibody
Mouse
ELISA, Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$1,001
PVRL3 / Nectin-3 Rat anti-Mouse Monoclonal (aa50-400) (FITC) (103-A1) Antibody
Mouse
Flo, Func, IF, IHC, IHC-Fr, IP
FITC Conjugated
100 µg/$807
PVRL3 / Nectin-3 Rat anti-Mouse Monoclonal (Concentrated) (103-A1) Antibody
Mouse
Flo, IHC, IHC-Fr, IP, WB
Unconjugated, Concentrated
1 ml/$786
PVRL3 / Nectin-3 Mouse anti-Human Monoclonal (6D5B2) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa467-516) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
PVRL3 / Nectin-3 Rat anti-Mouse Monoclonal (Extracellular Domain) (103-A1) Antibody
Mouse
Flo, Func, IF, IHC, IHC-Fr, IP
Unconjugated
100 µg/$652
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa143-192) Antibody
Human
WB
Unconjugated
100 µl/$424
PVRL3 / Nectin-3 Rat anti-Mouse Monoclonal (aa50-400) (FITC) (13A62) Antibody
Mouse
ELISA, Flo, Func, ICC, IHC, IHC-Fr, IP
FITC Conjugated
100 µg/$910
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
E. coli
His-T7
26.1 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
PVRL3 / Nectin-3 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$412
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PVRL3 / Nectin-3 Mouse anti-Human Monoclonal (1D1) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$412
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa507-536) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa507-536) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (311-360 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (160-240 aa, Internal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
PVRL3 / Nectin-3 Rabbit anti-Mouse Polyclonal (aa90-293) Antibody
Mouse, Rat
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa184-233) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa166-215) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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of 67
product results
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