PVR / CD155

poliovirus receptor

Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration. Serves as a receptor for poliovirus attachment to target cells. May play a role in axonal transport of poliovirus, by targeting virion-PVR-containing endocytic vesicles to the microtubular network through interaction with DYNLT1. This interaction would drive the virus-containing vesicle to the axonal retrograde transport.

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Products

Proteins (25)

Type

Over-Expression Lysate (6)

Recombinant (19)

Target

PVR / CD155 (25)

Publications

No (25)

Tag

10His, N-terminus (1)

6His, C-terminus (3)

6His-SUMO, N-terminus (1)

Fc, C-terminus (3)

GST (1)

GST, N-terminus (1)

His (1)

His,C-terminus (4)

His-T7 (2)

mFc, C-terminus (1)

Myc-DDK (Flag) (7)

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Species

Human (16)

Monkey-Rhesus (1)

Mouse (3)

Rat (2)

Source

293T Cells (3)

E. coli (4)

HEK 293 Cells (8)

Human Cells (3)

Mammalian Cells (5)

Wheat Germ Extract (2)

Purification

Purified (8)

Low Endotoxin Level

Low endotoxin level (12)

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Human PVR / CD155 Protein (Recombinant 6His, C-terminus) (Trp21-Asn343) - LS-G39096

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

36.13kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157

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Human PVR / CD155 Protein (Recombinant Fc, C-terminus) - LS-G145590

Source:

HEK 293 Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

85-105 kDa

Price:

100 µg/$423; 1 mg/$1,475

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Mouse PVR / CD155 Protein (Recombinant 6His, C-terminus) (Asp29-Leu348) - LS-G40334

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

35.6kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

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Human PVR / CD155 Protein (Recombinant GST) (Full Length) - LS-G30050

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

71.7 kDa

Price:

2 µg/$439

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Human PVR / CD155 Protein (Recombinant GST, N-terminus) (aa32-141) - LS-G59839

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PVR / CD155 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66622

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.1 kDa

Price:

20 µg/$1,107

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PVR / CD155 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100836

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.1 kDa

Price:

100 µg/$494

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PVR / CD155 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G125543

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.9 kDa

Price:

100 µg/$494

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PVR / CD155 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G125544

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.1 kDa

Price:

100 µg/$494

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Human PVR / CD155 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78127

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.9 kDa

Price:

20 µg/$150

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Human PVR / CD155 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78128

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.1 kDa

Price:

20 µg/$150

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Human PVR / CD155 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78130

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.1 kDa

Price:

20 µg/$150

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Human PVR / CD155 Protein (Recombinant mFc, C-terminus) (Trp21-Asn343) - LS-G138916

Source:

Mammalian Cells

Tag:

mFc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

61.7 kDa

Price:

10 µg/$266; 50 µg/$361

Select

Human PVR / CD155 Protein (Recombinant 10His, N-terminus) (Full Length) - LS-G136918

Source:

E. coli

Tag:

10His, N-terminus

Molecular Weight:

46.7 kDa

Price:

100 µg/$1,801; 20 µg/$1,247

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Mouse PVR / CD155 Protein (Recombinant 6His, C-terminus) (Asp29-Leu348) - LS-G139308

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

35.6 kDa

Price:

10 µg/$281; 50 µg/$389

Select

Human PVR / CD155 Protein (Recombinant Fc, C-terminus) (Trp21-Asn343) - LS-G139340

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

62.2 kDa

Price:

10 µg/$281; 50 µg/$389

Select

Human PVR / CD155 Protein (Recombinant His,C-terminus) (Trp21-Asn343) - LS-G139796

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

36.13 kDa

Price:

10 µg/$376; 50 µg/$526

Select

Monkey-Rhesus PVR / CD155 Protein (Recombinant His,C-terminus) (Met1-Asn343) - LS-G139974

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

35.4 kDa

Price:

10 µg/$297; 50 µg/$460

Select

Rat PVR / CD155 Protein (Recombinant His-T7) (aa22-255) - LS-G24356

Source:

E. coli

Tag:

His-T7

Molecular Weight:

29.0 kDa

Price:

10 µg/$289; 50 µg/$490; 100 µg/$782; 200 µg/$977; 1 mg/$2,114; 500 µg/$1,640; 5 mg/$3,417; 2 mg/$2,304

Select

Human PVR / CD155 Protein (Recombinant 6His-SUMO, N-terminus) (aa21-343) - LS-G56473

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

Select

Human PVR / CD155 Protein (Recombinant His,C-terminus) (Met1-Asn343) - LS-G138113

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

36.5 kDa

Price:

100 µg/$721; 1 mg/$4,701

Select

Human PVR / CD155 Protein (Recombinant Fc, C-terminus) (Met1-Asn343) - LS-G138114

Source:

HEK 293 Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

61.8 kDa

Price:

100 µg/$721; 1 mg/$4,701

Select

Mouse PVR / CD155 Protein (Recombinant His,C-terminus) (Met1-Arg345) - LS-G138166

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

28 kDa

Price:

100 µg/$721

Select

Rat PVR / CD155 Protein (Recombinant His) (Met1-Gly352) - LS-G98462

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

35.8 kDa

Price:

100 µg/$843

Select

Human PVR / CD155 Protein (Recombinant His-T7) (aa56-309) - LS-G13977

Source:

E. coli

Tag:

His-T7

Molecular Weight:

31.4 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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