PVR / CD155

poliovirus receptor

Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration. Serves as a receptor for poliovirus attachment to target cells. May play a role in axonal transport of poliovirus, by targeting virion-PVR-containing endocytic vesicles to the microtubular network through interaction with DYNLT1. This interaction would drive the virus-containing vesicle to the axonal retrograde transport.

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ELISA Kits (3)

Type

Sandwich (3)

Target

PVR / CD155 (3)

Reactivity

Human (3)

Format

96-Well Strip Plate (2)

Publications

No (2)

Yes (1)

Sample Type

Cell Culture Supernatants (1)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (2)

Serum (3)

Tissue Homogenates (1)

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Human PVR / CD155 (Sandwich ELISA) ELISA Kit - LS-F8103

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$798

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Human PVR / CD155 (Sandwich ELISA) ELISA Kit - LS-F65983

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human PVR / CD155 (Sandwich ELISA) ELISA Kit - LS-F57312

Type:

Sandwich

Reactivity:

Human

Range:

156 - 10000 pg/ml

Sample Types:

Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$699

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