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PTPRN2 / Phogrin

protein tyrosine phosphatase, receptor type, N polypeptide 2

PTPRN2 / Phogrin is a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants.

Gene Name: protein tyrosine phosphatase, receptor type, N polypeptide 2
Family/Subfamily: Protein Phosphatase , R8
Synonyms: PTPRN2, ICAAR, Ia-2 beta, IA-2beta, PTPRP, R-PTP-N2, Phogrin, Ptp-np, IAR, KIAA0387, PTP NE-6, Tyrosine phosphatase IA-2 beta
Target Sequences: NM_002847 NP_002838.2 Q92932

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Products
Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
PTPRN2 / Phogrin (8)
No (8)
GST, N-terminus (1)
His (2)
Myc-DDK (Flag) (3)
Human (5)
Mouse (2)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Yeast (2)
Purified (1)
PTPRN2 / Phogrin Protein
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Yeast
His
66.15 kD
1 mg/$1,607; 100 µg/$469; 20 µg/$349
PTPRN2 / Phogrin Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PTPRN2 / Phogrin Protein - Purified recombinant protein PTPRN2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
109.4 kDa
20 µg/$1,107
PTPRN2 / Phogrin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
109.4 kDa
100 µg/$710
PTPRN2 / Phogrin Protein - Recombinant Protein Tyrosine Phosphatase Receptor Type N2 (PTPRN2) by SDS-PAGE
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E. coli
None
28.7kDa
10 µg/$287; 50 µg/$482; 200 µg/$962; 100 µg/$770; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
PTPRN2 / Phogrin Protein - Recombinant Protein Tyrosine Phosphatase Receptor Type N2 (PTPRN2) by SDS-PAGE
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E. coli
None
24.0kDa
10 µg/$284; 50 µg/$462; 200 µg/$922; 100 µg/$737; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
PTPRN2 / Phogrin Protein
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Yeast
His
65.66 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
PTPRN2 / Phogrin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
109.4 kDa
20 µg/$215
Viewing 1-8 of 8 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).