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PTP4A3 is a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alternative splicing results in multiple transcript variants.
Gene Name: | protein tyrosine phosphatase type IVA, member 3 |
Family/Subfamily: | Protein Phosphatase , PTP4A |
Synonyms: | PTP4A3, PRL-R, PRL3, PRL-3 |
Target Sequences: | NM_032611 NP_116000.1 O75365 |
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