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PTP4A1 / PRL-1 is a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X.
Gene Name: | protein tyrosine phosphatase type IVA, member 1 |
Family/Subfamily: | Protein Phosphatase , PTP4A |
Synonyms: | PTP4A1, HH72, PTPCAAX1, PTP(CAAXI), PRL-1, PRL1, PTP(CAAX1) |
Target Sequences: | NM_003463 NP_003454.1 Q93096 |
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