PTP-PEST / PTPN12

protein tyrosine phosphatase, non-receptor type 12

PTP-PEST / PTPN12 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Products

Antibodies (34)

Proteins (9)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (2)

Primary (34)

Recombinant (6)

Target

PTP-PEST / PTPN12 (43)

Reactivity

Human (32)

Mouse (7)

Rat (8)

Chimpanzee (3)

Gibbon (3)

Guinea pig (3)

Monkey (4)

Orangutan (3)

Rabbit (3)

Application

IHC (9)

IHC-P (4)

WB (28)

ELISA (6)

ICC (1)

IF (1)

IP (6)

Peptide-ELISA (2)

Host

rabbit (32)

mouse (2)

Product Group

IHCPlus (1)

Isotype

IgG (16)

IgG1 (1)

IgG2a,k (1)

Clonality

monoclonal mc (2)

polyclonal pc (31)

recombinant monoclonal rmc (1)

Clone

4G6 (1)

Format

APC (1)

APC Conjugated (1)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (1)

Unconjugated (18)

Epitope

aa323-372 (4)

aa591-640 (4)

aa760-780 (2)

aa375-425 (1)

aa500-550 (1)

aa681-714 (1)

aa710-760 (1)

aa724-756 (1)

aa739-753 (1)

Publications

No (42)

Yes (1)

Tag

GST, N-terminus (1)

His, N-Terminal (2)

His-GST (1)

His-T7, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (8)

Source

293T Cells (1)

Baculovirus (2)

E. coli (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (4)

Supernatant (1)

Low Endotoxin Level

Low endotoxin level (2)

Select

PTP-PEST / PTPN12 Antibody (aa739-753) LS-C3352

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal (aa739-753) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$316

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Human PTP-PEST / PTPN12 Protein (Recombinant) (Met1-Gln355) - LS-G98645

Source:

Baculovirus

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

41.8 kDa

Price:

100 µg/$843

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PTP-PEST / PTPN12 Antibody LS-C17487

Antibody:

PTP-PEST / PTPN12 Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µl/$702

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IHC-plus™ PTP-PEST / PTPN12 Antibody (clone 4G6) LS-B6408

(4.0) Rating

Antibody:

PTP-PEST / PTPN12 Mouse anti-Human Monoclonal (4G6) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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PTP-PEST / PTPN12 Antibody (aa760-780) LS-C286506

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal (aa760-780) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

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Human PTP-PEST / PTPN12 Protein (Recombinant His, N-Terminal) (Glu2-Gln299) - LS-G96908

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

37 kDa

Price:

10 µg/$265; 200 µg/$484; 50 µg/$315

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Human PTP-PEST / PTPN12 Protein (Recombinant GST, N-terminus) (Full Length) - LS-G30042

(4.0) Rating

(1) Publication(s)

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Molecular Weight:

114.5 kDa

Price:

10 µg/$479; 25 µg/$670

Select

PTP-PEST / PTPN12 Antibody LS-C671029

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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PTP-PEST / PTPN12 Antibody LS-C836090

Antibody:

PTP-PEST / PTPN12 Rabbit Recombinant Monoclonal Antibody

Applications:

ICC, IHC, IP, WB

Format:

Unconjugated

Price:

20 µl/$299; 100 µl/$425

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PTP-PEST / PTPN12 Antibody (aa760-780) LS-C288112

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal (aa760-780) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

PTP-PEST / PTPN12 Antibody LS-C403458

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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PTP-PEST / PTPN12 Antibody (aa500-550) LS-C288110

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal (aa500-550) Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

PTP-PEST / PTPN12 Antibody (aa710-760) LS-C288111

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal (aa710-760) Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

PTP-PEST / PTPN12 Antibody LS-C137223

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$332

Select

PTP-PEST / PTPN12 Antibody (aa375-425) LS-C288107

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal (aa375-425) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

PTP-PEST / PTPN12 Antibody (aa724-756) LS-C393062

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal (aa724-756) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

Select

PTP-PEST / PTPN12 Antibody (aa681-714) LS-C393065

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal (aa681-714) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

Select

PTP-PEST / PTPN12 Antibody LS-C488858

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

PTP-PEST / PTPN12 Antibody (aa323-372) LS-C107660

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal (aa323-372) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

PTP-PEST / PTPN12 Antibody (aa323-372, HRP) LS-C461302

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal (aa323-372) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

PTP-PEST / PTPN12 Antibody (aa323-372, Biotin) LS-C461301

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal (aa323-372) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

PTP-PEST / PTPN12 Antibody (aa323-372, FITC) LS-C461300

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal (aa323-372) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

PTP-PEST / PTPN12 Antibody LS-C663339

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

Select

PTP-PEST / PTPN12 Antibody (FITC) LS-C694851

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716

Select

PTP-PEST / PTPN12 Antibody (Cy3) LS-C703551

Antibody:

PTP-PEST / PTPN12 Rabbit anti-Human Polyclonal (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

• Unconjugated
• FITC
• Cy3

• Unconjugated
• FITC
• Cy3

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