PTGS2 / COX2 / COX-2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.

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Products

Proteins (7)

Type

Recombinant (7)

Target

PTGS2 / COX2 / COX-2 (7)

Publications

No (6)

Yes (1)

Tag

6His, N-terminus (1)

GST (2)

His (1)

His, N-Terminal (1)

His,C-terminus (1)

His-T7 (1)

Species

Human (6)

Mouse (1)

Source

E. coli (4)

Insect Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

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Human PTGS2 / COX2 / COX-2 Protein (Recombinant 6His, N-terminus) (aa18-601) - LS-G21094

(4.1) Rating

(2) Publication(s)

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

70.9 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human PTGS2 / COX2 / COX-2 Protein (Recombinant GST) (Full Length) - LS-G30024

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

92.18 kDa

Price:

2 µg/$439

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Mouse PTGS2 / COX2 / COX-2 Protein (Recombinant His) (aa240-351) - LS-G12664

Source:

E. coli

Tag:

His

Molecular Weight:

14.6 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Human PTGS2 / COX2 / COX-2 Protein (Recombinant His, N-Terminal) (aa187-425) - LS-G12661

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

32.0 kDa

Price:

10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934

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Human PTGS2 / COX2 / COX-2 Protein (Recombinant GST) (Full Length) - LS-G30025

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

95.4 kDa

Price:

2 µg/$439

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Human PTGS2 / COX2 / COX-2 Protein (Recombinant His-T7) (aa418-589) - LS-G12665

Source:

E. coli

Tag:

His-T7

Molecular Weight:

22.6 kDa

Price:

10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934

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Human PTGS2 / COX2 / COX-2 Protein (Recombinant His,C-terminus) (Met1-Leu604) - LS-G140736

Source:

Insect Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

68.5 kDa

Price:

50 µg/$721

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