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Vector Laboratories, Inc.
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Newark, CA 94560
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PTGS1 / COX-1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.

Gene Name: prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
Synonyms: PTGS1, COX1, Cyclooxygenase-1, COX-1, PES-1, PGH synthase 1, Prostaglandin G/H synthase 1, PTGHS, COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS 1, PHS1, Prostaglandin H2 synthase 1
Target Sequences: NM_000962 NP_000953.2 P23219

Publications (1)

1
Inhibition of Pro-inflammatory and Anti-apoptotic Biomarkers during Experimental Oral Cancer Chemoprevention by Dietary Black Raspberries. Oghumu S, Casto BC, Ahn-Jarvis J, Weghorst LC, Maloney J, Geuy P, Horvath KZ, Bollinger CE, Warner BM, Summersgill KF, Weghorst CM, Knobloch TJ. Frontiers in immunology. 2017 October;8:1325. [Full Text Article] [PubMed:29109723] [PMC:PMC5660285]

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Products
ELISA Kits (23)
Cell-Based (1)
Competitive EIA (1)
Sandwich (19)
Sandwich CLIA (2)
PTGS1 / COX-1 (23)
Human (7)
Mouse (3)
Rat (6)
Bovine (1)
Chicken (1)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (2)
12 x 8-Well Microstrips (1)
96-Well Microplate (4)
96-Well Strip Plate (18)
No (22)
Yes (1)
Adherent Cell Cultures (1)
Plasma (18)
Serum (18)
Tissue Homogenates (8)
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.63 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$651
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$764
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$715
PTGS1 / COX-1 ELISA Kit
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Cell-Based
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
PTGS1 / COX-1 ELISA Kit
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Competitive EIA
96-Well Strip Plate
Bovine
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Microplate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Microplate
Rabbit
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
PTGS1 / COX-1 ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Rat
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
PTGS1 / COX-1 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
0.156 - 10 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
100 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
PTGS1 / COX-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
PTGS1 / COX-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$968
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).