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Vector Laboratories, Inc.
6737 Mowry Ave
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PTGS1 / COX-1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.
| Gene Name: | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| Synonyms: | PTGS1, COX1, Cyclooxygenase-1, COX-1, PES-1, PGH synthase 1, Prostaglandin G/H synthase 1, PTGHS, COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS 1, PHS1, Prostaglandin H2 synthase 1 |
| Target Sequences: | NM_000962 NP_000953.2 P23219 |
Publications (1)
1
Inhibition of Pro-inflammatory and Anti-apoptotic Biomarkers during Experimental Oral Cancer Chemoprevention by Dietary Black Raspberries. Oghumu S, Casto BC, Ahn-Jarvis J, Weghorst LC, Maloney J, Geuy P, Horvath KZ, Bollinger CE, Warner BM, Summersgill KF, Weghorst CM, Knobloch TJ. Frontiers in immunology. 2017 October;8:1325. [Full Text Article]
[PubMed:29109723]
[PMC:PMC5660285]
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PTGS1 / COX-1
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(89)
Neuroscience
PTGS1 / COX-1 Rabbit anti-Human Polyclonal (aa550-599) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
PTGS1 / COX-1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
PTGS1 / COX-1 Mouse anti-Human Monoclonal Antibody
Rabbit, Guinea pig, Sheep, Bovine, Human
ELISA, IHC
Unconjugated
1 ml/$626
PTGS1 / COX-1 Goat anti-Human Polyclonal (aa617-630) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
PTGS1 / COX-1 Mouse anti-Human Monoclonal (PE) (CX111) Antibody
Mouse, Sheep, Bovine, Rat, Human
Flo, IF
PE Conjugated
1 Each/$457
PTGS1 / COX-1 Mouse anti-Human Monoclonal Antibody
Mouse, Sheep, Rat, Human
ELISA, IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$740
PTGS1 / COX-1 Mouse anti-Human Monoclonal (HRP) Antibody
Mouse, Sheep, Rat, Human
ELISA, IF, IHC, WB
HRP Conjugated
100 µl/$982
PTGS1 / COX-1 Mouse anti-Human Monoclonal (Biotin) Antibody
Mouse, Sheep, Rat, Human
ELISA, IF, IHC, WB
Biotin Conjugated
100 µl/$982
PTGS1 / COX-1 Mouse anti-Human Monoclonal (FITC) Antibody
Mouse, Sheep, Rat, Human
ELISA, IF, IHC, WB
FITC Conjugated
100 µl/$982
PTGS1 / COX-1 Mouse anti-Human Monoclonal (APC) Antibody
Mouse, Sheep, Rat, Human
ELISA, IF, IHC, WB
APC Conjugated
100 µl/$982
PTGS1 / COX-1 Mouse anti-Human Monoclonal (PE) Antibody
Mouse, Sheep, Rat, Human
ELISA, IF, IHC, WB
PE Conjugated
100 µl/$982
PTGS1 / COX-1 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PTGS1 / COX-1 Rabbit anti-Human Polyclonal (aa318-599) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
PTGS1 / COX-1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
500 µl/$460
PTGS1 / COX-1 Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse, Dog, Human
ELISA, WB
Unconjugated
100 µg/$832
PTGS1 / COX-1 Rabbit anti-Human Polyclonal (aa218-267) Antibody
Human
WB
Unconjugated
100 µl/$424
PTGS1 / COX-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
100 µg/$442
PTGS1 / COX-1 Rabbit anti-Human Polyclonal (aa272-282) Antibody
Sheep, Bovine, Horse, Human
ICC, IHC, WB
Unconjugated
200 µl/$737
PTGS1 / COX-1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
PTGS1 / COX-1 Rabbit anti-Human Polyclonal (520-600 aa, C-terminal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PTGS1 / COX-1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Rat, Human
IF, WB
Biotin Conjugated
100 µg/$477
PTGS1 / COX-1 Rabbit anti-Human Polyclonal (RPE) Antibody
Mouse, Rat, Human
IF, WB
RPE Conjugated
100 µg/$477
PTGS1 / COX-1 Rabbit anti-Human Polyclonal (APC) Antibody
Mouse, Rat, Human
IF, WB
APC Conjugated
100 µg/$479
PTGS1 / COX-1 Rabbit anti-Human Polyclonal (Atto 390) Antibody
Mouse, Rat, Human
IF, WB
Atto 390 Conjugated
100 µg/$480
PTGS1 / COX-1 Rabbit anti-Human Polyclonal (Atto 594) Antibody
Mouse, Rat, Human
IF, WB
Atto 594 Conjugated
100 µg/$479
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