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Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.
Gene Name: | prostaglandin reductase 2 |
Synonyms: | PTGR2, PGR2, Prostaglandin reductase 2, PRG-2, ZADH1 |
Target Sequences: | AA443151 NP_689657.1 Q8N8N7 |
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