PTAFR / PAF Receptor

platelet-activating factor receptor

PTAFR / PAF Receptor is a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation, internalization, and down-regulation. Alternative splicing results in multiple transcript variants.

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Proteins (8)

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Over-Expression Lysate (8)

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PTAFR / PAF Receptor (8)

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No (8)

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Myc-DDK (Flag) (8)

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Human (4)

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293T Cells (4)

HEK 293 Cells (4)

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PTAFR / PAF Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99234

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39 kDa

Price:

100 µg/$494

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Human PTAFR / PAF Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80873

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39 kDa

Price:

20 µg/$150

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Human PTAFR / PAF Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80874

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39 kDa

Price:

20 µg/$150

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Human PTAFR / PAF Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80875

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39 kDa

Price:

20 µg/$150

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Human PTAFR / PAF Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80876

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39 kDa

Price:

20 µg/$150

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PTAFR / PAF Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G128605

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39 kDa

Price:

100 µg/$494

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PTAFR / PAF Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G128603

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39 kDa

Price:

100 µg/$494

Select

PTAFR / PAF Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G128604

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39 kDa

Price:

100 µg/$494

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