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PSPH belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome.
Gene Name: | phosphoserine phosphatase |
Synonyms: | PSPH, L-3-phosphoserine phosphatase, Phosphoserine phosphatase, PSPase, PSP, PSPHD |
Target Sequences: | NM_004577 NP_004568.2 P78330 |
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