PSMD1

proteasome (prosome, macropain) 26S subunit, non-ATPase, 1

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding. Alternatively spliced transcript variants have been found for this gene.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

PSMD1 (3)

Publications

No (3)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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Human PSMD1 Protein (Recombinant GST, N-terminus) (aa1-110) - LS-G59791

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PSMD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78296

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

105.7 kDa

Price:

20 µg/$150

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PSMD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99879

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

105.7 kDa

Price:

100 µg/$494

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