PSMC2 / RPT1

proteasome (prosome, macropain) 26S subunit, ATPase, 2

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Products

Antibodies (39)

Type

Primary (39)

Target

PSMC2 / RPT1 (39)

Reactivity

Human (39)

Mouse (20)

Rat (11)

Bovine (6)

Chimpanzee (3)

Dog (6)

Gibbon (6)

Guinea pig (6)

Monkey (6)

Orangutan (6)

Pig (6)

Rabbit (6)

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Application

IHC (8)

IHC-P (3)

WB (37)

ELISA (12)

ICC (3)

IF (8)

IP (3)

Peptide-ELISA (1)

Host

rabbit (34)

mouse (5)

Product Group

IHCPlus (1)

Isotype

IgG (19)

IgG1 (3)

IgG1,k (2)

Clonality

monoclonal mc (5)

polyclonal pc (34)

Clone

1851CT193.4.40 (1)

4C10-2C8 (1)

MSS1-104 (1)

MSS1-92 (1)

Format

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (21)

Epitope

N-Terminus (8)

aa1-433 (8)

aa1-30 (7)

aa150-200 (1)

Publications

No (39)

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PSMC2 / RPT1 Antibody (aa1-433) LS-C296082

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal (aa1-433) Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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IHC-plus™ PSMC2 / RPT1 Antibody (aa150-200) LS-B12916

(4.0) Rating

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal (aa150-200) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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PSMC2 / RPT1 Antibody LS-C482335

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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PSMC2 / RPT1 Antibody (N-Terminus) LS-C31036

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

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PSMC2 / RPT1 Antibody LS-C755233

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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PSMC2 / RPT1 Antibody LS-C331807

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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PSMC2 / RPT1 Antibody LS-C810252

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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PSMC2 / RPT1 Antibody (clone 4C10-2C8) LS-C198018

Antibody:

PSMC2 / RPT1 Mouse anti-Human Monoclonal (4C10-2C8) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

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PSMC2 / RPT1 Antibody LS-C769918

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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PSMC2 / RPT1 Antibody LS-C405163

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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PSMC2 / RPT1 Antibody LS-C401855

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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PSMC2 / RPT1 Antibody LS-C817056

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF

Format:

Unconjugated

Price:

100 µl/$412

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PSMC2 / RPT1 Antibody LS-C341398

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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PSMC2 / RPT1 Antibody LS-C137484

Antibody:

PSMC2 / RPT1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$445

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PSMC2 / RPT1 Antibody (clone 1851CT193.4.40) LS-C757581

Antibody:

PSMC2 / RPT1 Mouse anti-Human Monoclonal (1851CT193.4.40) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

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PSMC2 / RPT1 Antibody (aa1-30) LS-C330030

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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PSMC2 / RPT1 Antibody (aa1-30, Biotin) LS-C267300

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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PSMC2 / RPT1 Antibody (aa1-30, FITC) LS-C267301

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

PSMC2 / RPT1 Antibody (aa1-30, APC) LS-C267299

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

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PSMC2 / RPT1 Antibody (aa1-30, Azide-free, HRP) LS-C267302

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

PSMC2 / RPT1 Antibody (aa1-30, PE) LS-C267303

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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PSMC2 / RPT1 Antibody LS-C815693

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$412

Select

PSMC2 / RPT1 Antibody (clone MSS1-104) LS-C343793

Antibody:

PSMC2 / RPT1 Mouse anti-Human Monoclonal (MSS1-104) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$571

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PSMC2 / RPT1 Antibody (clone MSS1-92) LS-C343808

Antibody:

PSMC2 / RPT1 Mouse anti-Human Monoclonal (MSS1-92) Antibody

Reactivity:

Human

Applications:

IP

Format:

Unconjugated

Price:

25 µl/$335

Select

PSMC2 / RPT1 Antibody (N-Terminus) LS-C109885

Antibody:

PSMC2 / RPT1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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