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PSMB1

proteasome (prosome, macropain) subunit, beta type, 1

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species.

Gene Name: proteasome (prosome, macropain) subunit, beta type, 1
Family/Subfamily: Protease , Threonine T1
Synonyms: PSMB1, Macropain subunit C5, HC5, PMSB1, Proteasome gamma chain, Proteasome subunit beta 1, Proteasome beta 1 subunit, Proteasome component C5, Lmpc5, Proteasome subunit beta type-1, Proteasome subunit HC5, PSC5
Target Sequences: NM_002793 NP_002784.1 P20618

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
PSMB1 (6)
No (6)
GST (2)
His (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
PSMB1 Protein
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E. coli
His
100 µg/$511; 500 µg/$1,348; 20 µg/$311
PSMB1 Protein - 12.5% SDS-PAGE of human PSMB1 stained with Coomassie Blue
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Wheat Germ Extract
GST
52.9 kDa
10 µg/$479; 25 µg/$670
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E. coli
GST
50.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
PSMB1 Protein - Purified recombinant protein PSMB1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
26.3 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
26.3 kDa
20 µg/$150
PSMB1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
26.3 kDa
100 µg/$494
Viewing 1-6 of 6 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).