PSAP / Prosaposin

prosaposin

Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate.Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta-galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha-galactosidase A (EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases.Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12).Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.

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Products

Proteins (13)

Type

Over-Expression Lysate (6)

Recombinant (7)

Target

PSAP / Prosaposin (13)

Publications

No (13)

Tag

6His, N-terminus (1)

GST (3)

His (2)

His-T7 (1)

Myc-DDK (Flag) (6)

Species

Guinea pig (1)

Human (9)

Source

293T Cells (3)

E. coli (2)

HEK 293 Cells (3)

Human Cells (1)

Wheat Germ Extract (2)

Yeast (2)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (1)

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Human PSAP / Prosaposin Protein (Recombinant GST) (Full Length) - LS-G29957

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

81.29 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PSAP / Prosaposin Protein (Recombinant GST) (Full Length) - LS-G29958

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

83.16 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PSAP / Prosaposin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88771

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.11 kDa

Price:

20 µg/$215

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Human PSAP / Prosaposin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88773

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.11 kDa

Price:

20 µg/$150

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Human PSAP / Prosaposin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88769

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.48 kDa

Price:

20 µg/$215

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Human PSAP / Prosaposin Protein (Recombinant His) (Met1-Asn524) - LS-G97799

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

57.9 kDa

Price:

100 µg/$843

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PSAP / Prosaposin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99869

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.11 kDa

Price:

100 µg/$494

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PSAP / Prosaposin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119528

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.48 kDa

Price:

100 µg/$710

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PSAP / Prosaposin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119529

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.11 kDa

Price:

100 µg/$710

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Guinea pig PSAP / Prosaposin Protein (Recombinant His) (Full Length) - LS-G23090

Source:

Yeast

Tag:

His

Molecular Weight:

10.85 kD

Price:

100 µg/$679; 20 µg/$429; 1 mg/$1,973

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Human PSAP / Prosaposin Protein (Recombinant His-T7) (aa17-524) - LS-G25079

Source:

E. coli

Tag:

His-T7

Molecular Weight:

60.2 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Human PSAP / Prosaposin Protein (Recombinant GST) (aa311-391) - LS-G21087

Source:

E. coli

Tag:

GST

Molecular Weight:

36.4 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human PSAP / Prosaposin Protein (Recombinant 6His, N-terminus) (aa311-391) - LS-G57237

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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