PSAP / Prosaposin

prosaposin

Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate.Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta-galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha-galactosidase A (EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases.Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12).Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.

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Antibodies (44)

ELISA Kits (18)

Proteins (13)

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PSAP / Prosaposin (75)

Reactivity

Human (46)

Mouse (9)

Rat (8)

Chicken (2)

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mouse (8)

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monoclonal mc (9)

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Cell Culture Supernatants (2)

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IHC-plus™ PSAP / Prosaposin Antibody (clone 4D5F4) LS-B9363

(4.0) Rating

Antibody:

PSAP / Prosaposin Mouse anti-Human Monoclonal (4D5F4) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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PathPlus™ PSAP / Prosaposin Antibody (Internal) LS-B14263

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

PSAP / Prosaposin Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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Human PSAP / Prosaposin (Sandwich ELISA) ELISA Kit - LS-F6339

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Seminal Plasma

Price:

1 Plate/$730

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Human PSAP / Prosaposin (Sandwich ELISA) ELISA Kit - LS-F35235

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human PSAP / Prosaposin (Competitive EIA) ELISA Kit - LS-F27781

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

50 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$805

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PSAP / Prosaposin Antibody LS-C331707

Antibody:

PSAP / Prosaposin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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PathPlus™ PSAP / Prosaposin Antibody (clone 1D1-C12) LS-B5522

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

PSAP / Prosaposin Mouse anti-Human Monoclonal (1D1-C12) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µg/$485

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Human PSAP / Prosaposin (Sandwich ELISA) ELISA Kit - LS-F20872

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Rat PSAP / Prosaposin (Competitive EIA) ELISA Kit - LS-F28050

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

50 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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PSAP / Prosaposin Antibody (aa17-524) LS-B16786

Antibody:

PSAP / Prosaposin Rabbit anti-Human Polyclonal (aa17-524) Antibody

Reactivity:

Human

Applications:

ICC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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Mouse PSAP / Prosaposin (Sandwich ELISA) ELISA Kit - LS-F19218

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human PSAP / Prosaposin (CLIA) ELISA Kit - LS-F29228

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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PSAP / Prosaposin Antibody (Amino Acid: 325-524, clone 4D5F4) LS-C759693

Antibody:

PSAP / Prosaposin Mouse anti-Human Monoclonal (Amino Acid: 325-524) (4D5F4) Antibody

Reactivity:

Human

Applications:

Flo, ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$503

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PSAP / Prosaposin Antibody (clone PASE/4LJ) LS-C312155

Antibody:

PSAP / Prosaposin Mouse anti-Human Monoclonal (PASE/4LJ) Antibody

Reactivity:

Human

Applications:

IHC-Fr, IHC-P

Format:

Unconjugated

Price:

0.1 ml/$302

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PSAP / Prosaposin Antibody (clone 003, Preservative Free) LS-C819385

Antibody:

PSAP / Prosaposin Rabbit anti-Mouse Monoclonal (Preservative Free) (003) Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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IHC-plus™ PSAP / Prosaposin Antibody (aa307-356) LS-B13438

(4.0) Rating

Antibody:

PSAP / Prosaposin Rabbit anti-Human Polyclonal (aa307-356) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$515

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IHC-plus™ PSAP / Prosaposin Antibody (aa291-340) LS-B14689

(4.0) Rating

Antibody:

PSAP / Prosaposin Rabbit anti-Human Polyclonal (aa291-340) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

IHC-plus™ PSAP / Prosaposin Antibody LS-B12980

(4.0) Rating

Antibody:

PSAP / Prosaposin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

PSAP / Prosaposin Antibody LS-C755282

Antibody:

PSAP / Prosaposin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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PSAP / Prosaposin Antibody LS-C755283

Antibody:

PSAP / Prosaposin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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PSAP / Prosaposin Antibody LS-C755284

Antibody:

PSAP / Prosaposin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

PSAP / Prosaposin Antibody LS-C755286

Antibody:

PSAP / Prosaposin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

PSAP / Prosaposin Antibody LS-C755287

Antibody:

PSAP / Prosaposin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

PathPlus™ PSAP / Prosaposin Antibody (aa1-250) LS-B16396

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

PSAP / Prosaposin Rabbit anti-Human Polyclonal (aa1-250) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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PSAP / Prosaposin Antibody (clone PSPN1-1) LS-C489971

Antibody:

PSAP / Prosaposin Mouse anti-Human Monoclonal (PSPN1-1) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC

Format:

Unconjugated

Price:

20 µg/$371; 100 µg/$574

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