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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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PRTN3 / Myeloblastin
proteinase 3
Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
| Gene Name: | proteinase 3 |
| Family/Subfamily: | Protease , Serine S1 |
| Synonyms: | PRTN3, ACPA, Azurophil granule protein 7, C-ANCA antigen, CANCA, C-ANCA, AGP7, Leukocyte proteinase 3, MBN, Myeloblastin, NP-4, Neutrophil proteinase 4, NP4, p29, PR-3, Proteinase 3, MBT, Wegener autoantigen, PR3, Serine proteinase, neutrophil |
| Target Sequences: | NM_002777 NP_002768.3 P24158 |
Publications (4)
1
IL-1 and IL-36 are dominant cytokines in generalized pustular psoriasis. Johnston A, Xing X, Wolterink L, Barnes DH, Yin Z, Reingold L, Kahlenberg JM, Harms PW, Gudjonsson JE. The Journal of allergy and clinical immunology. 2017 July;140:109-120. [Full Text Article]
[PubMed:28043870]
[PMC:PMC5494022]
2
Membrane-Associated Proteinase 3 on Granulocytes and Acute Myeloid Leukemia Inhibits T Cell Proliferation. Yang TH, St John LS, Garber HR, Kerros C, Ruisaard KE, Clise-Dwyer K, Alatrash G, Ma Q, Molldrem JJ. Journal of immunology (Baltimore, Md. : 1950). 2018 September;201:1389-1399. [Full Text Article]
[PubMed:30021768]
[PMC:PMC6099529]
Related Antibodies: LS-C38480.
3
Inflammatory Proteins HMGA2 and PRTN3 as Drivers of Vulvar Squamous Cell Carcinoma Progression. Agnieszka Fatalska, Natalia Rusetska, Elwira Bakula-Zalewska, Artur Kowalik, Sebastian Zieba, Agnieszka Wroblewska, Kamil Zalewski, Krzysztof Goryca, Dominik Domanski, Magdalena Kowalewska. Cancers. 2020 December;13: [Full Text Article]
[PubMed:33374674]
[PMC:PMC7793473]
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Products
Antibodies
(75)
Type
Primary
(75)
Target
PRTN3 / Myeloblastin
(75)
Reactivity
Human
(59)
Mouse
(9)
Rat
(9)
Application
IHC
(16)
IHC-Fr
(5)
IHC-P
(6)
WB
(67)
Flo
(6)
ELISA
(20)
Func
(2)
ICC
(1)
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(1)
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(2)
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rabbit
(45)
mouse
(27)
goat
(1)
human
(1)
sheep
(1)
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IHCPlus
(2)
Isotype
Ig
(1)
IgG
(17)
IgG1
(5)
IgG2a
(10)
IgG2b
(11)
IgG2b,k
(1)
Clonality
monoclonal mc
(27)
polyclonal pc
(48)
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2F10
(1)
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(2)
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(2)
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(2)
OTI2H7
(2)
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(2)
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(2)
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(2)
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(2)
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(2)
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(3)
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(5)
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(1)
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(7)
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(6)
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(1)
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(3)
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(3)
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(9)
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(7)
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(5)
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(36)
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aa28-248
(12)
aa18-246
(8)
aa24-249
(8)
aa71-247
(8)
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(7)
aa76-125
(4)
C-Terminus
(2)
Internal
(1)
N-Terminus
(1)
aa26-249
(1)
aa88-98
(1)
Publications
No
(74)
Yes
(1)
PRTN3 / Myeloblastin Goat anti-Human Polyclonal (aa88-98) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
PRTN3 / Myeloblastin Human anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
2 ml/$522
PRTN3 / Myeloblastin Mouse anti-Human Monoclonal (WGM2) Antibody
Human
Flo, Func, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$652
PRTN3 / Myeloblastin Mouse anti-Human Monoclonal (FITC) (WGM2) Antibody
Human
Flo, Func, IHC, IHC-Fr, IHC-P, WB
FITC Conjugated
100 µg/$863
PRTN3 / Myeloblastin Mouse anti-Human Monoclonal (PR3-G2) Antibody
Human
Flo, IHC, IHC-Fr, WB
Unconjugated
100 µg/$554
PRTN3 / Myeloblastin Mouse anti-Human Monoclonal (FITC) (PR3-G2) Antibody
Human
Flo, IHC, IHC-Fr, WB
FITC Conjugated
100 µg/$617
PRTN3 / Myeloblastin Mouse anti-Human Monoclonal (aa28-248) (5B8) Antibody
Human
IHC, IHC-P
Unconjugated
50 µl/$440
PRTN3 / Myeloblastin Mouse anti-Human Monoclonal (Concentrated) (PRG-2) Antibody
Human
Flo, IHC, IHC-Fr, WB
Unconjugated, Concentrated
1 ml/$638
PRTN3 / Myeloblastin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PRTN3 / Myeloblastin Rabbit anti-Mouse Polyclonal (aa24-249) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
PRTN3 / Myeloblastin Rabbit anti-Mouse Polyclonal (aa24-249) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$345; 200 µl/$402; 500 µl/$594; 1 ml/$737; 2 ml/$976; 5 ml/$1,676
PRTN3 / Myeloblastin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IHC, IP, WB
Unconjugated
250 µl/$651
PRTN3 / Myeloblastin Rabbit anti-Human Polyclonal (aa76-125) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
PRTN3 / Myeloblastin Mouse anti-Human Monoclonal (aa28-248) (OTI9C2) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
PRTN3 / Myeloblastin Mouse anti-Human Monoclonal (aa28-248) (Carrier-free) (OTI9C2) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PRTN3 / Myeloblastin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
Flo, IHC, WB
Unconjugated
500 µg/$393
PRTN3 / Myeloblastin Mouse anti-Human Monoclonal (aa28-248) (OTI1D10) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
PRTN3 / Myeloblastin Mouse anti-Human Monoclonal (aa28-248) (Carrier-free) (OTI1D10) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PRTN3 / Myeloblastin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
PRTN3 / Myeloblastin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, WB
Unconjugated
500 µg/$393
PRTN3 / Myeloblastin Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
1 mg/$834
PRTN3 / Myeloblastin Mouse anti-Human Monoclonal (3B4) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$435
PRTN3 / Myeloblastin Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
PRTN3 / Myeloblastin Rabbit anti-Human Polyclonal (aa228-256) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
PRTN3 / Myeloblastin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$393
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of 75
product results
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