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PRSS8 / Prostasin is a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.
Gene Name: | protease, serine, 8 |
Family/Subfamily: | Protease , Serine S1 |
Synonyms: | PRSS8, Channel-activating protease 1, Prostasin, Serine protease 8, MCAP1, Protease, serine, 8 |
Target Sequences: | NM_002773 NP_002764.1 Q16651 |
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