PRSS2 / Trypsin 2

protease, serine, 2 (trypsin 2)

PRSS2 / Trypsin 2 belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.

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Products

Proteins (7)

Type

Recombinant (7)

Target

PRSS2 / Trypsin 2 (7)

Application

SDS-PAGE (1)

Publications

No (7)

Tag

6His, N-terminus (1)

GST (1)

His (3)

His, N-Terminal (1)

His,C-terminus (1)

Species

Human (3)

Mouse (3)

Rat (1)

Source

E. coli (4)

HEK 293 Cells (1)

Human Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (4)

Biologically Active

Biologically active (1)

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Mouse PRSS2 / Trypsin 2 Protein (Recombinant 6His, N-terminus) (aa29-240) - LS-G13954

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

26.6 kDa

Price:

10 µg/$277; 50 µg/$417; 100 µg/$667; 200 µg/$832; 1 mg/$1,922; 500 µg/$1,470; 5 mg/$2,913; 2 mg/$2,107

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Human PRSS2 / Trypsin 2 Protein (Recombinant His, N-Terminal) (aa24-241) - LS-G24349

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

27.0 kDa

Price:

10 µg/$279; 50 µg/$430; 100 µg/$687; 200 µg/$857; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142

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Mouse PRSS2 / Trypsin 2 Protein (Recombinant His,C-terminus) (Met1-Asn246) - LS-G49384

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant pro form of mouse PRSS2 comprises 242 amino acids and has a predicted molecular mass of 26.2 kDa. The apparent molecular mass of rm PRSS2 is approximately 32 kDa in SDS-PAGE under reducing conditions.

Price:

50 µg/$441

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Mouse PRSS2 / Trypsin 2 Protein (Recombinant His) (Met1-Asn246) - LS-G98309

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

26.2 kDa

Price:

50 µg/$854

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Human PRSS2 / Trypsin 2 Protein (Recombinant His) (aa16-247) - LS-G140987

Source:

E. coli

Sequence Length:

231 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

25.52 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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Rat PRSS2 / Trypsin 2 Protein (Recombinant His) (aa24-246) - LS-G140883

Source:

E. coli

Sequence Length:

222 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

24.53 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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Human PRSS2 / Trypsin 2 Protein (Recombinant GST) (Full Length) - LS-G29949

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

52.9 kDa

Price:

10 µg/$479; 25 µg/$670

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