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PRPSAP2 is a protein that associates with the enzyme phosphoribosylpyrophosphate synthetase (PRS). PRS catalyzes the formation of phosphoribosylpyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, histidine, tryptophan and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits. This gene encodes a non-catalytic associated subunit of PRS. Alternate splicing results in multiple transcript variants.
Gene Name: | phosphoribosyl pyrophosphate synthetase-associated protein 2 |
Synonyms: | PRPSAP2, PAP41 |
Target Sequences: | NM_002767 NP_002758.1 O60256 |
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