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The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. This gene product is one of several proteins that associate with U4 and U6 snRNPs. Mutations in this gene are associated with retinitis pigmentosa-18.
Gene Name: | pre-mRNA processing factor 3 |
Synonyms: | PRPF3, HPRP3, RP18, Pre-mRNA-splicing factor 3, HPRP3P, PRP3, Prp3p, U4/U6 snRNP 90 kDa protein |
Target Sequences: | NM_004698 NP_004689.1 O43395 |
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