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This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.
Gene Name: | prolactin receptor |
Synonyms: | PRLR, HPRL receptor, PRL-R, HPRLrI, Prolactin receptor |
Target Sequences: | NM_000949 NP_000940.1 P16471 |
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