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PRKY is similar to the protein kinase, X-linked gene in the pseudoautosomal region of the X chromosome. The gene is classified as a transcribed pseudogene because it has lost a coding exon that results in all transcripts being candidates for nonsense-mediated decay (NMD) and unlikely to express a protein. Abnormal recombination between this gene and a related gene on chromosome X is a frequent cause of XX males and XY females.
Gene Name: | protein kinase, Y-linked, pseudogene |
Family/Subfamily: | Protein Kinase , cAMP |
Synonyms: | PRKY, PRKXP3, PRKYP, Protein kinase, Y-linked, Protein kinase Y linked |
Target Sequences: | NM_002760 NP_002751.1 O43930 |
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