PRKAR2A

protein kinase, cAMP-dependent, regulatory, type II, alpha

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

PRKAR2A (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human PRKAR2A Protein (Recombinant His) - LS-G3266

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human PRKAR2A Protein (Recombinant GST) (Full Length) - LS-G29902

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

69.5 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PRKAR2A Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65159

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.3 kDa

Price:

20 µg/$1,107

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Human PRKAR2A Protein (Recombinant GST, N-terminus) (aa1-105) - LS-G59725

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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PRKAR2A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100221

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.3 kDa

Price:

100 µg/$494

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Human PRKAR2A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74970

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.3 kDa

Price:

20 µg/$150

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