PRKAG2 / AMPK Gamma 2

protein kinase, AMP-activated, gamma 2 non-catalytic subunit

AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.

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Products

Antibodies (27)

Proteins (8)

Type

Over-Expression Lysate (4)

Primary (27)

Recombinant (4)

Target

PRKAG2 / AMPK Gamma 2 (35)

Reactivity

Human (19)

Mouse (16)

Rat (4)

Monkey (1)

Application

IHC (10)

IHC-P (4)

WB (23)

ELISA (5)

ICC (2)

IF (5)

Peptide-ELISA (2)

Host

rabbit (27)

Isotype

IgG (16)

Clonality

polyclonal pc (27)

Format

APC (1)

APC Conjugated (2)

Biotin Conjugated (2)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (2)

Unconjugated (15)

Epitope

aa290-508 (8)

N-Terminus (2)

10-90 aa, N-terminal (1)

aa1-50 (1)

aa192-569 (1)

aa386-569 (1)

pSer60 (1)

Publications

No (35)

Tag

6His, N-terminus (1)

GST (1)

GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (4)

Species

Human (5)

Mouse (1)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

Select

PRKAG2 / AMPK Gamma 2 Antibody (aa386-569) LS-C186349

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal (aa386-569) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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PRKAG2 / AMPK Gamma 2 Antibody (aa1-50) LS-C119303

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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PRKAG2 / AMPK Gamma 2 Antibody (N-Terminus) LS-C358248

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human, Monkey

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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PRKAG2 / AMPK Gamma 2 Antibody (N-Terminus) LS-C3638

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$786

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PRKAG2 / AMPK Gamma 2 Antibody (HRP) LS-C543431

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$1,017

Select

PRKAG2 / AMPK Gamma 2 Antibody (APC) LS-C515046

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$1,017

Select

PRKAG2 / AMPK Gamma 2 Antibody (PE) LS-C651543

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$1,017

• Unconjugated
• HRP
• APC
• PE

• Unconjugated
• HRP
• APC
• More...
  • PE

Select

PRKAG2 / AMPK Gamma 2 Antibody (aa192-569) LS-C186045

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal (aa192-569) Antibody

Reactivity:

Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

Select

PRKAG2 / AMPK Gamma 2 Antibody (10-90 aa, N-terminal) LS-C382012

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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PRKAG2 / AMPK Gamma 2 Antibody LS-C660102

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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PRKAG2 / AMPK Gamma 2 Antibody LS-C823267

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

100 µg/$357

Select

PRKAG2 / AMPK Gamma 2 Antibody LS-C749285

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

PRKAG2 / AMPK Gamma 2 Antibody LS-C832247

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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PRKAG2 / AMPK Gamma 2 Antibody (phospho-Ser60) LS-C20506

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal (pSer60) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$688

Select

PRKAG2 / AMPK Gamma 2 Antibody LS-C801684

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

PRKAG2 / AMPK Gamma 2 Antibody (aa290-508) LS-C296124

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Mouse Polyclonal (aa290-508) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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PRKAG2 / AMPK Gamma 2 Antibody (aa290-508, HRP) LS-C712438

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Mouse Polyclonal (aa290-508) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

Select

PRKAG2 / AMPK Gamma 2 Antibody (aa290-508, Biotin) LS-C687826

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Mouse Polyclonal (aa290-508) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

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PRKAG2 / AMPK Gamma 2 Antibody (aa290-508, FITC) LS-C694719

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Mouse Polyclonal (aa290-508) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765

Select

PRKAG2 / AMPK Gamma 2 Antibody (aa290-508, Cy3) LS-C703413

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Mouse Polyclonal (aa290-508) (Cy3) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

Select

PRKAG2 / AMPK Gamma 2 Antibody (aa290-508, PE) LS-C726500

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Mouse Polyclonal (aa290-508) (PE) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

Select

PRKAG2 / AMPK Gamma 2 Antibody (aa290-508, APC) LS-C741013

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Mouse Polyclonal (aa290-508) (APC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

Select

PRKAG2 / AMPK Gamma 2 Antibody (aa290-508, APC, Cy7) LS-C735429

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Mouse Polyclonal (aa290-508) (APC, Cy7) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781

• Unconjugated
• HRP
• Biotin
• FITC
• Cy3
• PE
• APC
• More...
  • APC, Cy7

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • Cy3
  • PE
  • APC
  • APC, Cy7

Select

PRKAG2 / AMPK Gamma 2 Antibody LS-C833285

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

PRKAG2 / AMPK Gamma 2 Antibody LS-C749481

Antibody:

PRKAG2 / AMPK Gamma 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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