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PRKACB

protein kinase, cAMP-dependent, catalytic, beta

Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.

Gene Name: protein kinase, cAMP-dependent, catalytic, beta
Family/Subfamily: Protein Kinase , cAMP
Synonyms: PRKACB, Cbeta, PKACB, PKA C-beta, PKA Cbeta
Target Sequences: NM_002731 NP_002722.1 P22694

Publications (1)

1
Protein Kinase A in Human Retina: Differential Localization of Cß, Ca, RIIa, and RIIß in Photoreceptors Highlights Non-redundancy of Protein Kinase A Subunits. Jinae N Roa, Yuliang Ma, Zbigniew Mikulski, Qianlan Xu, Ronit Ilouz, Susan S Taylor, Dorota Skowronska-Krawczyk. Frontiers in molecular neuroscience. 2021 December;14:782041. [Full Text Article] [PubMed:34867193] [PMC:PMC8636463] Related Antibodies: LS-C191947.

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ELISA Kits (10)
Cell-Based (1)
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PRKACB (10)
Human (4)
Mouse (3)
Rat (3)
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96-Well Microplate (2)
96-Well Strip Plate (8)
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Adherent Cell Cultures (1)
Plasma (3)
Serum (3)
Tissue Homogenates (3)
PRKACB ELISA Kit
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Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
PRKACB ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PRKACB ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PRKACB ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PRKACB ELISA Kit
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Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
PRKACB ELISA Kit
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Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
PRKACB ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
PRKACB ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
PRKACB ELISA Kit
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Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$669
PRKACB ELISA Kit
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Custom
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
1 Plate/$823
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).