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The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit.
Gene Name: | primase, DNA, polypeptide 1 (49kDa) |
Synonyms: | PRIM1, DNA primase subunit 48, DNA primase 1, Dna primase 49 kd subunit, DNA primase 49 kDa subunit, p49, Primase polypeptide 1, 49kDa, DNA primase small subunit, Primase p49 subunit |
Target Sequences: | NM_000946 NP_000937.1 P49642 |
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