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PRDM16
PR domain containing 16
Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation.
| Gene Name: | PR domain containing 16 |
| Synonyms: | PRDM16, KIAA1675, MDS1/EVI1-like gene 1, MEL1, PFM13, Transcription factor MEL1, PR domain containing 16 |
| Target Sequences: | NM_022114 |
Publications (1)
1
Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis. Qinjie Weng, Jincheng Wang, Jiajia Wang, Danyang He, Zuolin Cheng, Feng Zhang, Ravinder Verma, Lingli Xu, Xinran Dong, Yunfei Liao, Xuelian He, Andrew Potter, Liguo Zhang, Chuntao Zhao, Mei Xin, Qian Zhou, Bruce J Aronow, Perry J Blackshear, Jeremy N Rich, Qiaojun He, Wenhao Zhou, Mario L Suvà, Ronald R Waclaw, S Steven Potter, Guoqiang Yu, Q Richard Lu. Cell stem cell. 2019 May;24:707-723e8. [Full Text Article]
[PubMed:30982771]
[PMC:PMC6669001]
Related Antibodies: LS-B4625.
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(14)
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(14)
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PRDM16
(14)
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(14)
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(6)
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(12)
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(6)
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monoclonal mc
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(13)
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aa539-588
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aa771-804
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Publications
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(13)
Yes
(1)
PRDM16 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
PRDM16 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
PRDM16 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
PRDM16 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
PRDM16 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
PRDM16 Rabbit anti-Human Polyclonal Antibody
Human
IHC
Unconjugated
100 µg/$393
PRDM16 Rabbit anti-Human Polyclonal (aa771-804) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
PRDM16 Mouse anti-Human Monoclonal (1740CT793.52.44) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$393
PRDM16 Goat anti-Human Polyclonal (aa1264-1276) Antibody
Human, Monkey
Flo, Peptide-ELISA
Unconjugated
100 µg/$503
PRDM16 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PRDM16 Rabbit anti-Human Polyclonal (aa539-588) Antibody
Human
WB
Unconjugated
100 µl/$424
PRDM16 Rabbit anti-Human Polyclonal (aa539-588) (HRP) Antibody
Mouse, Dog, Guinea pig, Horse, Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
PRDM16 Rabbit anti-Human Polyclonal (aa539-588) (Biotin) Antibody
Mouse, Dog, Guinea pig, Horse, Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
PRDM16 Rabbit anti-Human Polyclonal (aa539-588) (FITC) Antibody
Mouse, Dog, Guinea pig, Horse, Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
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