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PPY / Pancreatic Polypeptide

pancreatic polypeptide

PPY / Pancreatic Polypeptide belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.

Gene Name: pancreatic polypeptide
Family/Subfamily: Pancreatic hormone , not assigned-Pancreatic hormone
Synonyms: PPY, Obinepitide, Pancreatic polypeptide Y, Pancreatic prohormone, PP, Pancreatic polypeptide, Pancreatic hormone
Target Sequences: NM_002722 NP_002713.1 P01298

Publications (4)

1
Establishment of an enzyme-linked immunosorbent assay for mouse pancreatic polypeptide clarifies the regulatory mechanism of its secretion from pancreatic ? cells. Daisuke Saito, Yuko Nakagawa, Takashi Sato, Ayako Fukunaka, Ofejiro Blessing Pereye, Nobuhiro Maruyama, Hirotaka Watada, Yoshio Fujitani. PloS one. 2022 August;17:e0269958. [Full Text Article] [PubMed:35976945] [PMC:PMC9385059]
2
Distinctive expression and cellular distribution of dopamine receptors in the pancreatic islets of rats. Chen Y, Hong F, Chen H, Fan RF, Zhang XL, Zhang Y, Zhu JX. Cell and tissue research. 2014 Sep;357:597-606. [Full Text Article] [PubMed:24825414] Related Antibodies: LS-B5911.
3
New perspectives of vesicular monoamine transporter 2 chemical characteristics in mammals and its constant expression in type 1 diabetes rat models. Hong F, Liu L, Fan RF, Chen Y, Chen H, Zheng RP, Zhang Y, Gao Y, Zhu JX. Translational research : the journal of laboratory and clinical medicine. 2014 Feb;163:171-82. [Full Text Article] [PubMed:24161354] Related Antibodies: LS-B5911.
4
Differential expression and localization of neuropeptide Y peptide in pancreatic islet of diabetic and high fat fed rats. Ruipan Z, Xiangzhi M, Li L, Ying Z, Mingliang Q, Peng J, Jingwei L, Zijun Z, Yan G. Peptides. 2014 Apr;54:33-8. [Full Text Article] [PubMed:24462552] Related Antibodies: LS-B5911.
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Antibodies (48)
Primary (48)
PPY / Pancreatic Polypeptide (48)
Human (37)
Mouse (11)
Rat (5)
Bovine (1)
Monkey (1)
IHC (5)
IHC-Fr (1)
IHC-P (5)
WB (37)
Flo (2)
ELISA (20)
IF (1)
Peptide-ELISA (2)
rabbit (33)
mouse (13)
goat (2)
Product Group
IHCPlus (2)
PathPlus Other (1)
IgG (15)
IgG1 (10)
IgG1,k (1)
IgG2a (2)
monoclonal mc (13)
polyclonal pc (35)
2C10-C7-H5-C9-G9 (2)
2C11-F11-F6-G8-E11-G10 (2)
2G5D12 (2)
4C1-E11-E10-F2 (2)
GF1 (1)
OTI1G2 (2)
OTI1G7 (2)
APC (2)
APC Conjugated (2)
Biotin Conjugated (8)
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Cy3 Conjugated (2)
Cy7 Conjugated (2)
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HRP Conjugated (2)
PE Conjugated (2)
Preservative Free (6)
Unconjugated (28)
aa30-87 (8)
aa31-97 (8)
aa30-88 (4)
Amino Acid: 1-95 (1)
aa30-95 (1)
aa61-73 (1)
No (47)
Yes (1)
PPY / Pancreatic Polypeptide Antibody - Anti-PPY antibody IHC of human intestine, neuroendocrine cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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PPY / Pancreatic Polypeptide Goat anti-Human Polyclonal (aa61-73) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
PPY / Pancreatic Polypeptide Antibody - Western blot using PPY monoclonal antibody against human PPY recombinant protein. (Expected MW is 35.9 kDa)
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PPY / Pancreatic Polypeptide Mouse anti-Human Monoclonal (2G5D12) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
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PPY / Pancreatic Polypeptide Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$508; 100 µg/$860
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PPY / Pancreatic Polypeptide Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µg/$241; 100 µg/$303; 200 µg/$334; 500 µg/$452
PPY / Pancreatic Polypeptide Antibody - Western blot of recombinant PPY / Pancreatic Polypeptide.
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PPY / Pancreatic Polypeptide Rabbit anti-Mouse Polyclonal (aa31-97) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
PPY / Pancreatic Polypeptide Antibody - Western blot of recombinant PPY / Pancreatic Polypeptide.
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PPY / Pancreatic Polypeptide Rabbit anti-Mouse Polyclonal (aa31-97) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$345; 200 µl/$402; 500 µl/$594; 1 ml/$737; 2 ml/$976; 5 ml/$1,676
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PPY / Pancreatic Polypeptide Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA
Unconjugated
200 µg/$1,027
PPY / Pancreatic Polypeptide Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PPY / Pancreatic Polypeptide Rabbit anti-Human Polyclonal (aa30-87) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
PPY / Pancreatic Polypeptide Antibody - Human Pancreas, Islet of Langerhans: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PPY / Pancreatic Polypeptide Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
0.5 ml/$485
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PPY / Pancreatic Polypeptide Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC
Unconjugated
50 µl/$572
PPY / Pancreatic Polypeptide Antibody - PPY Antibody in Western Blot (WB)
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PPY / Pancreatic Polypeptide Mouse anti-Human Monoclonal (Amino Acid: 1-95) (2G5D12) Antibody
Human
Flo, WB
Unconjugated
100 µg/$503
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PPY / Pancreatic Polypeptide Mouse anti-Human Monoclonal (2C10-C7-H5-C9-G9) Antibody
Human
ELISA, WB
Unconjugated
20 µg/$241; 100 µg/$303; 200 µg/$334; 500 µg/$452
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PPY / Pancreatic Polypeptide Mouse anti-Human Monoclonal (Biotin) (2C10-C7-H5-C9-G9) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$343
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PPY / Pancreatic Polypeptide Mouse anti-Human Monoclonal (2C11-F11-F6-G8-E11-G10) Antibody
Human
ELISA, WB
Unconjugated
20 µg/$241; 100 µg/$303; 200 µg/$334; 500 µg/$452
Select
PPY / Pancreatic Polypeptide Mouse anti-Human Monoclonal (Biotin) (2C11-F11-F6-G8-E11-G10) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$343
Select
PPY / Pancreatic Polypeptide Mouse anti-Human Monoclonal (4C1-E11-E10-F2) Antibody
Human
ELISA, WB
Unconjugated
20 µg/$241; 100 µg/$303; 200 µg/$334; 500 µg/$452
Select
PPY / Pancreatic Polypeptide Mouse anti-Human Monoclonal (Biotin) (4C1-E11-E10-F2) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$343
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PPY / Pancreatic Polypeptide Rabbit anti-Bovine Polyclonal (Concentrated) Antibody
Bovine
IHC, IHC-Fr, IHC-P
Unconjugated, Concentrated
50 µl/$529
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PPY / Pancreatic Polypeptide Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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PPY / Pancreatic Polypeptide Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
Select
PPY / Pancreatic Polypeptide Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
Select
PPY / Pancreatic Polypeptide Rabbit anti-Human Polyclonal (Preservative Free) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated, Preservative Free
50 µg/$343
PPY / Pancreatic Polypeptide Antibody - Western blot analysis of Rat pancreas tissue lysate  using PPY Polyclonal Antibody at dilution of 1:1900
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PPY / Pancreatic Polypeptide Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PPY / Pancreatic Polypeptide Antibody - Western blot analysis of Rat pancreas tissue lysate  using PPY Polyclonal Antibody at dilution of 1:2500
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PPY / Pancreatic Polypeptide Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
PPY / Pancreatic Polypeptide Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).