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Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins.
Gene Name: | palmitoyl-protein thioesterase 2 |
Synonyms: | PPT2, PPT-2, Lysosomal thioesterase PPT2, VE-statin2, C6orf8, G14, Palmitoyl-protein hydrolase 2, S-thioesterase G14 |
Target Sequences: | NM_005155 NP_005146.4 Q9UMR5 |
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